Автореферат (1097598), страница 10
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Goltsov A, Tashkandi G, Langdon SP, Harrison DJ, Bown JL. Kinetic modelling of in vitro dataof PI3K, mTOR1, PTEN enzymes and on-target inhibitors Rapamycin, BEZ235, and LY294002.European Journal of Pharmaceutical Sciences, 97 (2017) 170–181.2. Bown, J.L., Shovman, M., Robertson, P., Boiko, A., Goltsov, A., Mullen, P., Harrison, D.J., Asignaling visualization toolkit to support rational design of combination therapies and biomarkerdiscovery: SiViT. Oncotarget. 2017; 8:29657-29667. doi: 10.18632/oncotarget.87473. Semyachkina-Glushkovskaya O.V., Sokolovski S.G., Goltsov A., Gekaluyk A.S., SarancevaE.I., Bragina O.A., Tuchin V.V., Rafailov E.U. Laser-induced generation of singlet oxygen andits role in the cerebrovascular physiology.
Progress in Quantum Electronics, 2017, 25 May,doi.org/10.1016/j.pquantelec.2017.05.0014. Goltsov A., Anisimova A.V., Zakharkina M., Krupatkin A.I., Sidorov V.V., Sokolovski S.G.,Rafailov E.U. Bifurcation in blood oscillatory rhythms for patients with ischemic stroke: a smallscale clinical trial using laser Doppler flowmetry and computational modelling of vasomotion.Frontiers in Physiology, 23 March 2017 doi.org/10.3389/fphys.2017.00160.5. Khalil, H.S., Langdon, S.P., Goltsov, A., Soininen, T., Harrison, D.J., Bown, J., Deeni, Y.Y., Anovel mechanism of action of HER2 targeted immunotherapy is explained by inhibition of NRF2function in ovarian cancer cells. Oncotarget 2016.
2016 Nov 15;7(46):75874-75901. doi:10.18632/oncotarget.12425.6. Khalil HS, Goltsov A, Langdon SP, Harrison DJ, Bown J, Deeni Y. Quantitative analysis of NRF2pathway reveals key elements of the regulatory circuits underlying antioxidant response andproliferation of ovarian cancer cells. J Biotechnology, 11, 2014; DOI:10.1016/j.jbiotec.2014.09.0277. Goltsov, A, Langdon SP, Goltsov G, Harrison DJ, Bown J. Customizing the therapeutic responseof signaling networks to promote antitumor responses by drug combinations.
Front. Oncol. 2014,4, 13.8. Sokolovski S, Zolotovskaya S, Goltsov A, Pourreyron C, South A, Rafailov E. Infrared laserpulse triggers increased singlet oxygen production in tumour cells. Scientific Reports, 2013,3:3484.9. Sokolovski SG, Goltsov A, Rafailov EU. Modelling the hypersensitivity of cancer cells to infrared laser pulse: breaking ROS defence machinery.
Proc. SPIE 8568, Optical Methods for TumorTreatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXII, 85680E,2013, doi:10.1117/12.2001715.3610. Hu H, Goltsov A, Bown J, Sims AH, Langdon SP, Harrison DJ, Faratian D. Feedforward andfeedback regulation of the MAPK and PI3K oscillatory circuit in breast cancer.
Cellular Signalling.2013 Jan;25(1):26-32.11. Goltsov A, Faratian D, Langdon SP, Harrison DJ, Bown J. Features of the reversible sensitivityresistance transition in ERK/PI3K/PTEN/AKT signalling network at HER2 inhibition. CellularSignalling. 2012 Feb;24(2):493-504.12. Lebedeva G, Sorokin A, Faratian D, Mullen P, Goltsov A, Langdon SP, Harrison DJ, Goryanin I.Model-based global sensitivity analysis as applied to identification of anti-cancer drug targets andbiomarkers of drug resistance in the ErbB2/3 network.
Eur J Pharm Sci. 2012, Jul 16;46(4):24458.13. Bown J, Andrews PS, Deeni Y, Goltsov A, Idowu M, Polack FAC, Sampson AT, Shovman M,Stepney S. Engineering simulations for cancer systems biology. Curr Drug Targets. 2012Nov;13(12):1560-74.14. Tummala H, Goltsov A, Khalil HS, Sproul A, Scott F, Mitev V, Zhelev N. Advocating the needof prediction models for individualized prognosis and treatment in B-CLL disease patients.BioDiscovery 2012, Dec 6: 3.15.
Goltsov A, Faratian D, Langdon SP, Bown J, Goryanin I, Harrison DJ. Compensatory effects inthe PI3K/PTEN/AKT signaling network following receptor tyrosine kinase inhibition. CellularSignalling. 2011, 23, 407-416.16. Goltsov A, Lebedeva G, Humphery-Smith I, Goltsov G, Demin O, Goryanin I. In Silico Screeningof Nonsteroidal Anti-Inflammatory Drugs and Their Combined Action on Prostaglandin HSynthase-1. Pharmaceuticals 2010, 3, 2059-2081.17.
Faratian D, Goltsov A, Lebedeva G, Moodie S, Mullen P, Kay C, Um IH, Langdon S, GoryaninI, and Harrison DJ. Systems biology reveals new strategies for personalising cancer medicine andconfirms PTENs role in resistance to trastuzumab, Cancer Research 2009, 69, 6713.18. Goltsov A, Maryashkin A, Swat M, Kosinsky Y, Humphery-Smith I, Demin O, Goryanin I,Lebedeva G. Kinetic modelling of NSAID action on COX-1: Focus on in vitro/in vivo aspects anddrug combinations. European Journal of Pharmaceutical Sciences, 36, 2009, 122-136.Публикации автора в рецензируемых научных изданиях, индексируемых в базах данныхPubMed и Science Citation Index, опубликованные по теме диссертации19.
Adams R, Clark A, Yamaguchi A, Hanlon N, Tsorman N, Ali S, Lebedeva G, Goltsov A, SorokinA, Akman OE, Troein C, Millar AJ, Goryanin I, Gilmore S. SBSI: An extensible distributedsoftware infrastructure for parameter estimation in systems biology. Bioinformatics.
2013 Mar1;29(5):664-5.20. Goltsov A., Deeni Y., Khalil H.S., Soininen T., Kyriakidis S., Hu H., Simon Langdon P., HarrisonD.J. and Bown J. Systems Analysis of Drug-Induced Receptor Tyrosine Kinase ReprogrammingFollowing Targeted Mono- and Combination Anti-Cancer Therapy. Cells 2014, 3(2), 563-591;doi:10.3390/cells3020563.37Главы в коллективных монографиях1. Goltsov A, Deeni Y, Khalil H, Idowu M, Kyriakidis S, Goltsov G, Langdon SP, Harrison DJ,Bown J. Role of Post-translational Regulation of PTEN Activity in Cancer Cell Addiction toHeterozygous PTEN Mutations. In book PTEN: Structure, Mechanisms-of-Action, Role in CellSignaling and Regulation.
Editors: Ke Xu. Nova Science Publishers, 2013 (pp. 173-210)2. Goltsov, A, Langdon SP, Goltsov G, Harrison DJ, Bown J. Customizing the therapeutic responseof signaling networks to promote antitumor responses by drug combinations. In e-book DrugDiagnostics Co-Development in Oncology. Ed. JT Jørgensen. Frontiers in Oncology. 2014, ISBN978-2-88919-332-53. Bown J, Deeni Y, Goltsov A, Khalil H, Isaacs J, Li Y, Sampson AT, Savage A., Zhelev N. Cancersystems biology: Integrating experimental and theoretical systems at cellular and tissue scales.
Inbook Current Application of Biotechnology. Ed. M. Dundar, 357-386, Erciyes UniversityPublishing, 2015, ISBN: 978-605-85579-0-1.38.
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