the ayurvedic pharmacopoeia of india - ccras ( pdfdrive ) (830801), страница 17
Текст из файла (страница 17)
.Extract 4 g of cūr´a in alcohol(25 ml x 3) under reflux on a water-bath for 30min, filter, concentrate to 10 ml and carry out the thin layer chromatography Apply 10 µlof the extrct on TLC plate and develop the plate to a distance of 8 cm using toluene :ethyl acetate (5 : 1.5) as mobile phase. After development allow the plate to dry in air andexamine under ultraviolet light (254 nm). It shows major spots at Rf 0.26, 0.31, 0.43 (allblue) and 0.91 (fluorescent blue).Physico-chemical Parameters:Loss on drying at 1050:2.2.10.Total ash:2.2.3.Acid-insoluble ash:2.2.4.Alcohol-soluble extractive:2.2.7.Water-soluble extractive:2.2.8.pH (10% aqueous solution):Not more than 6 per cent,AppendixNot more than 56 per cent,AppendixNot more than 14 per cent,AppendixNot less than 11 per cent,AppendixNot less than 12 per cent,Appendix3 to 4,Appendix 3.3.Assay:Iron:5.2.5.Not less than 33 per cent,AppendixOther requirements:Microbial limit:Aflatoxin:Appendix 2.4.Appendix 2.7.Storage: Store in a cool place in tightly closed containers, protected from light andmoisture.Therapeutic uses:disorder);Skin); Arśa (piles).P¢´²u (anaemia); Kāmalā (jaundice); Prameha (metabolicPī²aka (carbuncle); H¨droga (heart disease); Ku¾°ha (diseases ofDose: 2 g daily in divided doses.Anupāna: Honey, Water.(AFI, Part-I, 7:20)NIMBĀDI CŪR³ADefinition:Nimbādi Cūr´a is a powder preparation made with the ingredients in the Formulation composition givenbelow:Formulation composition:1.2.3.4.5.6.7.8.9.10.11.12.Nimba APIAm¨tā (Gu²ūcī API)Abhayā (Harītakī API)Dhātrī (Āmalakī API)Somarājī (Bākucī API)Śu´°hī APIVi²a¬ga APIE²agaja (Cakramarda API)Ka´ā (Pippalī API)Yamānī (Yavānī API)Ugragandhā (Vacā API)Jīraka (Śveta Jīraka API)Azadirachta indicaTinospora cordifoliaTerminalia chebulaEmblica officinalisPsoralea corylifoliaZingiber officinaleEmbelia ribesCassia toraPiper longumTrachyspermum ammiAcorus calamusCuminum cyminumSt.
Bk.St.P.P.Fr.Rz.Fr.Sd.Fr.Fr.Rz.Fr.48 g48 g48 g48 g48 g12 g12 g12 g12 g12 g12 g12 g13.14.1516Ka°ukā APIKhadira APISaindhava Lava´a APIK¾āra (Yava API)Picrorrhiza kurroaAcacia catechuRock saltHordeum vulgare12 g12 g12 g12 g1718192021Haridrā APIDāruharidrā APIMustaka (Mustā API)Devadāru APIKu¾°ha APICurcuma longaBerberis aristataCyperus rotundusCedrus deodaraSaussurea lappaRt./Rz.Ht. Wd.Water solubleash of Pl.Rz.St.Rt. Tr.Ht.
Wd.Rt.12 g12 g12 g12 g12 gMethod of preparation:Roast coarsely powdered Saindhava lava´a (number 15) in a stainless steel pan at a lowtemperature till it becomes free from moisture. Prepare fine powder and pass throughsieve number 85. Clean, dry and powder the other ingredients 1 to 21 (except number 15)individually in a pulverizer and sift through sieve number 85 mesh separately.
Weighseparately each ingredient, mix together in specified ratio and pass through sieve number44 to obtain a homogeneous blend. Pack it in tightly closed containers to protect fromlight and moisture.Description:Yellowish brown, smooth powder, taste bitter, salty and odour pungent. The powdercompletely pass on through sieve number 44 and not less than 50 per cent pass onthrough sieve number 85.Identification:Thin Layer Chromatography:Extract 4 g of curna in alcohol (25 ml x 3) under reflux on a water-bath for 30 min filter, concentrate to 10ml and carry out the Thin Layer Chromatography.
Apply 10 µl of the extract on TLC plate and develop theplate to a distance of 8 cm using toluene : ethyl acetate (5 : 3) as mobile phase. After development of theplate, allow it to dry in air and examine under ultraviolet light (254 nm). It shows major spots at Rf 0.25(fluorescent blue), 0.52 (yellow), 0.67and 0.82, (both blue). Under ultraviolet light (366 nm), it showsmajor spots at Rf 0.25, 0.52, 0.57, 0.62, 0.72 and 0.82 (all pale blue). Spray the plate withvanillin-sulphuric acid reagent followed by heating at 1100 for about 10 min and observe under visiblelight.
The plate shows major spots at Rf 0.72 (grey), 0.82 (pink) and 0.87 (grey).Test for chloride: Dissolve 1 g of the sample in 10 ml of purified water and filter. Acidifythe filtrate with dilute nitric acid and add 5 per cent w/v silver nitrate solution. A curdywhite precipitate shows the presence of chlorides.Physico-chemical parameters:Loss on drying at 1050:Total ash:2.2.3.Acid-insoluble ash:2.2.4.Alcohol-soluble extractive:2.2.7.Water-soluble extractive:2.2.8.pH (10% aqueous solution):Not more than 8 per cent,2.2.10.Not more than 12 per cent,AppendixAppendixNot more than 10 per cent,AppendixNot less than 18 per cent,AppendixNot less than 23 per cent,Appendix4 to 5,Appendix 3.3.Not less than 0.6 per cent w/w,AppendixAssay:Sodium:5.2.9.Other requirementsMicrobial limits:Aflatoxins:Appendix 2.4.Appendix 2.7.Storage: Store in a cool place in tightly closed containers, protected from light and moisture.Therapeutic uses: Udara (diseases of abdomen); Āmavāta (Rheumatism); Vātarakta(Gout); Ku¾°ha (diseases of skin).Dose: 5 g daily in divided dose.Anupāna: Gu²ūcī kvātha, Warm water.PAÑCASAMA CŪR³A(AFI, Part-I, 7:22)Definition:Pa®casama Cūr´a is a powder preparation made with the ingredients in the Formulation composition givenbelow:Formulation composition:1.2.3.4.5.Śu´°hī APIHarītakī APIK¨¾´ā (Pippalī API)Triv¨t APISauvarcala lava´a APIZingiber officinaleRz.1 partTerminalia chebulaPiper longumP.Fr.1 part1 partIpomoea turpethumRt.1 partBlack salt-1 partMethod of preparation:Take the ingredients of pharmacopoeial quality.Wash, dry and powder the cleaned ingredients 1 to 4 individually in a pulverizer alsopowder ingredients 5 and sift separately through sieve number 85.
Weigh separately eachpowdered ingredient, mix together in specified ratio and pass through sieve number 44 toobtain a homogeneous blend.Pack it in tightly closed containers to protect from light and moisture.Description:Pale brown, smooth powder, odour pungent and taste slightly pungent with tinglingsensation. The powder completely pass on through sieve number 44 and not less than 50per cent pass on through sieve number 85.Identification:Microscopy:Take about 2 g of the Cūr´a and wash it thoroughly with water to remove the salt withoutloss of Cūr´a; using the washed Cūr´a make the following preparations: warm a few mgin chloral hydrate, wash to remove chloral hydrate and mount in glycerine; mount a fewmg in glycerine; treat a few mg with solution of iodine solution and mount in glycerine:take a few mg in a watch glass add iodine water, and drain excess of iodine by filterpaper; add a drop of sulphuric acid (2 parts in 1 part water), mount in glycerine to locatecellulosic fibres.
Observe the following characters in the different mounts:Fragments of septate non-lignified fibres, broad spiral and reticulate vessels and ovalshaped starch grains upto 50 µ in size (Śu´thī); groups of elongated thick walledsclereids with pits and broad lumen, crisscross thin walled fibres with broad lumen andpegged tips, polygonal epidermal cells with slight beading and dividing septum(Harītakī); uniseriate, multicellular trichomes, perisperm cells packed with starch grainsand minute crystals of calcium oxalate, isolated, elongated stone cells with broad lumen(Pippalī); Prismatic crystals of calcium oxalate and rosette crystals of calcium oxalate,vessels with regular bordered pits appearing like honey comb, stone cells and thick walledcellulosic fibres with broken ends and very narrow lumen (Triv¨t).Thin Layer Chromatography:.Extract 4 g of sample in alcohol (25 ml x 3) under reflux on a water-bath for 30 min filterconcentrate to 10 ml and carry out the Thin Layer Chromatography.
Apply 10 µl of the extract on TLCplate and develop the plate to a distance of 8 cm using toluene : ethyl acetate (5 : 2) as mobile phase. Afterdevelopment of the plate, allow it to dry in air and examine under ultraviolet light (254 nm). It shows majorspots at Rf 0.46 and 0.63 (both green). Under ultraviolet light (366 nm), it shows a major spot at Rf 0.77(fluorescent blue). Spray the plate with vanillin-sulphuric acid reagent followed by heating at 1100 forabout 10 min and observe under ultraviolet light. The plate shows a major spot at Rf 0.77 (pink).Physico-chemical parameters:Loss on drying at 1050: Not more than 10 per cent,Total ash:Not more than 22 per cent,Acid-insoluble ash:Not more than 3 per cent,Alcohol-soluble extractive:Not less than 20 per cent,Water-soluble extractive:Not less than 35 per cent,pH (10% aqueous solution): 4.5 to 4.7,Appendix 2.2.10.Appendix 2.2.3.Appendix 2.2.4.Appendix 2.2.7.Appendix 2.2.8.Appendix 3.3.Assay:Sodium:Not less than 4 per cent w/w,Appendix 5.2.9.Other requirements:Microbial limits:Aflatoxins:Appendix 2.4.Appendix 2.7.Storage: Store in a cool place in tightly closed containers, protected from light and moisture.Therapeutic uses: Ādhmāna (flatulence with gurgling sound); Śūla (pain / colic); Āmavāta (Rheumatism);Arśa (Piles); Udara roga (diseases of abdomen), Vibandha (constipation).Dose: 3 to 5 g daily in divided dose.Anupāna: Warm water.(AFI, Part-I, 7:23)PU½YĀNUGA CŪR³ADefinition:Pu¾yānuga Cūr´a is a powder preparation made with the ingredients in the Formulationcomposition given below.Formulation composition:1.Pā°hā API2.1 part3.1 part4.1 part5.6.1 part7.1 part8.1 part9.1 part10.1 part11.1 part12.1 part13.1 part14.1 part15.1 part16.1 part17.1 partJambū-bīja majjā APICissampelos pareira1 partSyzygium cuminiĀmra-bīja majjā APIMangifera indicaEnm.Śilābheda (Pā¾ā´abheda API)Bergenia ligulataRz.Rasā®jana APIAmba¾°hakī APIBerberis aristataHibiscus sabdariffaRt.Enm.Rt./St.
![](https://s.studizba.com/z.php?f=/templates/si/i/noavatar.png&w=100&h=100&t=1"){kind=avatar}
