the ayurvedic pharmacopoeia of india - ccras ( pdfdrive ) (830801), страница 15
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If so,specific precautions should be taken during storage.Cūr´as should be stored in air tight containers. Polyethylene and foil packing alsoprovides damp proof protection.Special precaution for storage should be taken in cases of formulations with salts, sugarsand Ks$āras.ĀMALAKYĀDI CŪR³A(AFI, Part-I, 7:3)Definition:Āmalakyādi Cūr´a is a powder preparation made with the ingredients in the Formulationcomposition given below.Formulation composition:1.Āmla (Āmalakī API)2.3.4.5.Citraka APIPathyā (Harītakī API)Pippalī APISaindhava lava´a APIPhyllanthus emblica(Emblica officinalis)Plumbago zeylanicaTerminalia chebulaPiper logumRock saltP.1 partRt.P.Fr.-1 part1 part1 part1 partMethod of preparation:Take all ingredients of pharmacopoeial quality.Roast Saindhava lava´a in a stainless steel pan at low temperature till it becomes freefrom moisture, prepare fine powder and pass through sieve number 85.Wash and dry the ingredients numbered 1 to 5, powder individually in a pulverizer andpass through sieve number 85.
Weigh separately each ingredient, mix together and passthrough sieve number 44 to obtain a homogeneous blend. Store it in an air-tight container.Pack it in tightly closed containers to protect from light and moisture.Description:Brown-coloured, smooth powder with pleasant odour and salty, spicy taste.
The powdercompletely pass on through sieve number 44 and not less than 50 per cent pass onthrough sieve number 85.Identification:Microscopy:Take about 2 g of Cūr´a, and wash it thoroughly with water to remove salt, pour out thewater without loss of material and mount in glycerine; warm a few mg with chloralhydrate, wash and mount in glycerine; treat a few mg with iodine in potassium iodidesolution and mount in glycerine. Observe the following characters in the differentmounts.Thin walled epidermis with paracytic stomata, brachysclereids with pitted wide lumen,silica crystals in epidermal cells (Āmalakī); cork cells in surface view, uniseriate andmultiseriate ray parenchyma cells, bifurcated short fibres and pitted vessels (Citraka);Prismatic and druses of calcium oxalate crystals, groups of sclereids, criss-cross layers offibres, thin walled fibres and broad lumen with pegged tip (Harītakī); perisperm cellspacked with starch grains and minute crystals of calcium oxalate, uniseriate multicellulartrichomes (Pippalī).Thin Layer Chromatography:Extract 4 g of cūr´a in alcohol (25 ml x 3) under reflux on a water-bath for 30 min, filter,concentrate to 10 ml and carry out the thin layer chromatography.
Apply 10 µl of theextract on TLC plate and develop the plate to a distance of 8 cm using toluene : ethylacetate (5 : 2) as mobile phase. After development, allow the plate to dry in air andexamine under ultraviolet light (254 nm). It shows major spots at Rf. 0.43 (light green),0.50 (green) and 0.85 (pale green).Test for chloride:Dissolve 1 g of the sample in 10 ml of deionised water and filter. Acidify the filtrate withdilute nitric acid and add 5 per cent w/v silver nitrate solution. A curdy white precipitateappears.Physico-chemical parameters:Loss on drying at 1050:2.2.10.Total ash:2.2.3.Acid-insoluble ash:2.2.4.Alcohol-soluble extractive:2.2.7.Water-soluble extractive:2.2.8.pH (10% aqueous solution):Not more than 10 per cent,AppendixNot more than 27 per cent,AppendixNot more than 0.6 per cent,AppendixNot less than 25 per cent,AppendixNot less than 46 per cent,Appendix3 to 4,Appendix 3.3.Not less than 6 per cent w/w,AppendixAssay:Sodium:5.2.9.Other requirements:Microbial limits:Aflatoxin:Appendix 2.4.Appendix 2.7.Storage: Store in a cool place in tightly closed containers, protected from light andmoisture.Therapeutic Uses:(indigestion).Aruci (anorexia); Agnimāndya (dyspepsia); Jvara (Fever); Aj¤r´aDose: 5 to 10 g daily in divided doses.Anupāna: Water.AVIPATTIKARA CŪR³A(AFI, Part- I, 7:2)Definition:Avipattikara Cūr´a is a powder preparation made with the ingredients in the Formulationcomposition given below.Formulation composition:1.2.3.4.5.6.Śu´°hī APIMarica APIPippalī APIHarītakī APIBibhītaka APIĀmalakī APIRz.Fr.Fr.P.P.P.1 part1 part1 part1 part1 part1 partMustā APIVi²ā lavanaVi²a¬ga APIElā (Sūk¾mailā API)Patra (Tejapatra API)Lava¬ga APIZingiber officinalePiper nigrumPiper longumTerminalia chebulaTerminalia belliricaPhyllanthus emblica(Emblica offcinalis)Cyperus rotundusEmbelia ribesEletteria cardamomumCinnamomum tamalaSyzygium aromaticum7.8.9.10.11.12.parts13.parts14.partsRz.Fr.Sd.Lf.Fl.
Bd.1 part1 part1 part1 part1 part11Triv¨t APIIpomoea turpethumRt.44Śarkarā APICane sugar-66Method of preparation:Take all ingredients of pharmacopoeial quality.Clean, dry and powder the ingredients numbered 1 to 7 and 9 to 13 individually in apulverizer and pass through sieve number 85. Prepare fine powder of Vi²a lavana andŚarkarā separately and pass through sieve number 85. Weigh separately each powderedingredient, mix together in specified ratio and pass through sieve number 44 to obtain ahomogeneous blend.
Pack it in tightly closed containers to protect from light andmoisture.Description:Light brown, fine powder, odour characteristic of clove, with a sweet, spicy andpungent taste. The powder completely pass on through sieve number 44 and not less than50 per cent pass on through sieve number 85.Identification:Thin Layer Chromatography:Extract 4 g of sample in alcohol (25 ml x 3) under reflux on a water-bath for 30 min,filter, concentrate to 10 ml and carry out the thin layer chromatography. Apply 10 µl ofthe extract on TLC plate and develop the plate to a distance of 8 cm using toluene : ethylacetate (5 : 2) as mobile phase.
After development allow the plate to dry in air andexamine under ultraviolet (366 nm). It shows major spots at Rf 0.11, 0.23, 0.35 (all blue)and 0.72 (fluorescent blue). Spray the plate with vanillin-sulphuric acid reagent followedby heating at 1100 for about 10 min and observe under visible light. The plate showsmajor spots at Rf 0.49, 0.54, (both violet), 0.65 and 0.73 (both pale violet).Test for Chloride:Dissolve 1 g of the sample in 10 ml of deionised water and filter.
Acidify the filtrate withdilute nitric acid and add 5 per cent w/v silver nitrate solution. A curdy white precipitateappears.Physico-chemical parameters:Loss on drying at 1050:2.2.10.Total ash:2.2.3.Acid- insoluble ash:2.2.4.Alcohol-soluble extractive:2.2.7.Water-soluble extractive:2.2.8.pH (10%) aqueous solution:Total sugars:5.1.3.2.Reducing sugars:5.1.3.1.Not more than 7 per cent,AppendixNot more than 6 per cent,AppendixNot more than 0.5 per cent,AppendixNot less than 20 per cent,AppendixNot less than 53 per cent,Appendix4 to 6,Not less than 39 per cent,Appendix 3.3.AppendixNot less than 4 per cent,AppendixOther requirements:Microbial load:Aflatoxin:Appendix 2.4.Appendix 2.7.Storage: Store in a cool place in tightly closed containers, protected from light andmoisture.Therapeutic uses: Agnimāndya (digestive impairment); Malabandha (constipation);Amlapitta (Hyperacidity); Arśa (Piles); Mūtrabandha (retention of urine); Prameha(metabolic disorder).Dose: 10 g daily in divided doses.Anupāna: Honey, Water, Milk.BĀLACĀTURBHADRIKĀ CŪR³A(AFI, Part-I, 7:24)Definition:Bālacaturbhadrikā Cūr´a is a powder preparation made with the ingredients in the Formulationcomposition given below:Formulation composition:1.2.3.Ghana (Mustā API)K¨¾´ā (Pippalī API)Aru´ā (Ativi¾ā API)Cyperus rotundusRt.Tr.Piper longumFr.Aconitum heterophyllum Rt.
Tr.1 part1 part1 part4.Ś¨¬gī (Karka°aś¨¬gī API)Pistacia integerrima1 partGl.Method of preparation:Take all the ingredients of pharmacopoeial quality.Clean, dry and powder the ingredients 1 to 4 individually and pass through sieve number85. Weigh separately each ingredient, mix together in specified ratio and pass throughsieve number 44 to obtain a homogeneous blend. Pack it in tightly closed containers toprotect from light and moisture.Description:Pale brown powder, odour characteristic of pippali and taste slightly pungent followed bya tingling sensation.
The powder completely pass on through sieve number 44 and notless than 50 per cent pass on through sieve number 85.Identification:Microscopy:Take a few mg of Cūr´a and warm with chloral hydrate, wash and mount in glycerine;wash a few mg of Cūr´a in water and mount in glycerine; treat a few mg of Cūr´a withiodine solution and mount in glycerine; observe the following characters in the differentmounts.Parenchyma cells with reddish brown contents, starch grains simple, circular to oval upto30 µ, narrow vessels with lateral simple perforation, walls reticulate, pitted and spiralvessels, regularly arranged sclereids from scale leaf (Mustā); multicellular uniseriatetrichomes, perisperm cells packed with starch grains and minute crystals of calciumoxalate, spindle shaped, elongated stone cells with wide lumen (Pippalī); starch grains,simple and compound with 2 to 4 components, upto 65µ in size, parenchyma cells withstarch grains and cork cells in surface view (Ativi¾ā); collapsed thin walled epidermalcells, tissue fragments with yellowish brown contents and large tannin containing sacsassociated with vascular bundles (Karka°aś¨¬gī).Thin Layer Chromatography:Extract 4 g of Cūr´a in alcohol (25 ml x 3) under reflux on a water-bath for 30 min filter, concentrate to 10ml and carry out the thin layer chromatography.
Apply 10 µl of the extract on TLC plate and develop theplate to a distance of 8cm using toluene : ethyl acetate (5 : 1.5) as mobile phase. After development allowthe plate to dry in air and examine under ultraviolet light (254 nm). It shows major spots at Rf 0.31, 0.37,0.45, 0.60 (all green), 0.74 (light green) and 0.91 (blue). Under ultraviolet light (366 nm), it shows majorspot at Rf 0.65 (fluorescent blue). Spray the plate with vanillin-sulphuric acid reagent followed by heatingat 1100 for about 10 min and observe under visible light. The plate shows major spots at Rf 0.36, 0.50 (bothgrey), 0.61 (blue), 0.68 (grey) and 0.81 (pink).Physico-chemical parameters:Loss on drying at 1050:Total ash:Not more than 9 per cent,Not more than 7 per cent,Acid-insoluble ash:2.2.4.Not more than 2.5 per cent,Alcohol-soluble extractive: Not less than 14 per cent,Water-soluble extractive:Not less than 16 per cent,pH (10% aqueous solution): 5 to 5.3,Appendix 2.2.10.Appendix 2.2.3.AppendixAppendix 2.2.7.Appendix 2.2.8.Appendix 3.3.Other requirements:Microbial limits:Aflatoxins:Appendix 2.4.Appendix 2.7.Storage: Store in a cool place in tightly closed containers, protected from light and moisture.Therapeutic uses: Atisāra (Diarrhoea); Chardi (Vomiting); Kāsa (cough); Śvāsa (Dyspnoea); Jvara (fever);Bāla śo¾a (emaciation in children).Dose: 0.5 to 1 g daily in divided dose.Anupāna: Honey.ELĀDI CŪR³A(AFI, Part-I, 7:5)Definition:Elādi Cūr´a is a powder preparation made with the ingredients in the Formulationcomposition given below.Formulation composition:1.2.3.4.5.6.7.8.9.Elā (Sūk¾mailā API)Lava¬ga APIGajakeśara (Nāgakeśara API)Kola majjā (Kola API)Lāja (Śāli API)Priya¬gu APIGhana (Mustā API)Candana (Śveta candana API)Pippalī APIElettaria cardamomumSyzygium aromaticumMesua ferreaZizyphus jujubaOryza sativaCallicarpa macrophyllaCyperus rotundusSantalum albumPiper longumSd.Fl.
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