Van Eyk, Dunn - Proteomic and Genomic Analysis of Cardiovascular Disease - 2003 (522919), страница 98
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M., Elghannam, H., Gotto, A. M., Jr., Marian, A. J. 2001. Novel polymorphisms inpromoter region of atp binding cassettetransporter gene and plasma lipids, severity, progression, and regression of coronary atherosclerosis and response totherapy. Circ. Res. 88:969–973.Clee, S. M., et al.
2000. Age and residualcholesterol efflux affect HDL cholesterollevels and coronary artery disease inABCA1 heterozygotes. J. Clin. Invest.106:1263–1270.Cavelier, L. B., et al. 2001. Regulationand activity of the human ABCA1 genein transgenic mice. J. Biol. Chem.276:18 046–18 051.Joyce, C. W., et al.
2002. The ATP binding cassette transporter A1 (ABCA1)modulates the development of aorticatherosclerosis in C57BL/6 and apoEknockout mice. Proc. Natl. Acad. Sci.USA 99:407–412.Vaisman, B. L., et al. 2001. ABCA1 overexpression leads to hyperalphalipoproteinemia and increased biliary cholesterolexcretion in transgenic mice. J. Clin. Invest. 108:303–309.Singaraja, R. R., et al.
2001. HumanABCA1 BAC transgenic mice show increased high density lipoprotein cholesterol and ApoAI-dependent efflux stimulated by an internal promoter containingliver X receptor response elements in intron 1. J. Biol. Chem. 276:33 969–33 979.Orso, E., et al. 2000. Transport of lipidsfrom golgi to plasma membrane is defec-35535620 Genomics Perspective for Drug Discovery43444546474849505152tive in tangier disease patients and Abc1deficient mice.
Nat. Genet. 24:192–196.McNeish, J., et al. 2000. High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruptionof ATP-binding cassette transporter-1.Proc. Natl. Acad. Sci. USA 97:4245–4250.Yokoyama, S., Kurasawa, T., Nishikawa,O., Yamamoto, A. 1986.
High density lipoproteins with poor reactivity to cholesteryl ester transfer reaction observed in ahomozygote of familial hyperalphalipoproteinemia. Artery 14:43–51.Kurasawa, T., Yokoyama, S., Miyake, Y.,Yamamura, T., Yamamoto, A. 1985. Rateof cholesteryl ester transfer between highand low density lipoproteins in humanserum and a case with decreased transferrate in association with hyperalphalipoproteinemia. J. Biochem. (Tokyo)98:1499–1508.Drayna, D., et al. 1987. Cloning and sequencing of human cholesteryl estertransfer protein cDNA. Nature 327:632–634.Herrera, V. L., et al.
1999. Spontaneouscombined hyperlipidemia, coronary heartdisease and decreased survival in Dahlsalt-sensitive hypertensive rats transgenicfor human cholesteryl ester transfer protein. Nat. Med. 5 :1383–1389.Inazu, A., et al. 1994. Genetic cholesterylester transfer protein deficiency causedby two prevalent mutations as a majordeterminant of increased levels of highdensity lipoprotein cholesterol. J. Clin.Invest 94:1872–1882.Okamoto, H., et al. 2000.
A cholesterylester transfer protein inhibitor attenuatesatherosclerosis in rabbits. Nature406:203–207.Kogushi, M., et al. 1996. Anti-atherosclerotic effect of E5324, an inhibitor of acylCoA:cholesterol acyltransferase, in Watanabe heritable hyperlipidemic rabbits.Atherosclerosis 124:203–210.Hoeg, J.
M., et al. 1996. Overexpressionof lecithin:cholesterol acyltransferase intransgenic rabbits prevents diet-inducedatherosclerosis. Proc. Natl. Acad. Sci.USA 93:11 448–11 453.Chao, J., Chao, L. 1996. Functional analysis of human tissue kallikrein in trans-5354555657585960616263genic mouse models. Hypertension27:491–494.Wang, C., Chao, L., Chao, J. 1995. Direct gene delivery of human tissue kallikrein reduces blood pressure in spontaneously hypertensive rats.
J. Clin. Invest.95:1710–1716.Yayama, K., Wang, C., Chao, L., Chao,J. 1998. Kallikrein gene delivery attenuates hypertension and cardiac hypertrophy and enhances renal function inGoldblatt hypertensive rats. Hypertension31:1104–1110.Kim, H. S., et al. 1995. Genetic control ofblood pressure and the angiotensinogenlocus. Proc. Natl.
Acad. Sci. USA92:2735–2739.Makino, N., Sugano, M., Ohtsuka, S.,Sawada, S., Hata, T. 1999. Chronic antisense therapy for angiotensinogen oncardiac hypertrophy in spontaneously hypertensive rats. Cardiovasc. Res 44:543–548.Tang, X., et al. 1999. Intravenous angiotensinogen antisense in AAV-based vector decreases hypertension. Am.J. Physiol.277:H2392–H2399.Tomita, N., et al.
1995. Transient decrease in high blood pressure by in vivotransfer of antisense oligodeoxynucleotides against rat angiotensinogen. Hypertension 26:131–136.Krege, J. H., et al. 1995. Male-female differences in fertility and blood pressure inACE-deficient mice. Nature 375:146–148.Esther, C. R., Jr., et al. 1996. Mice lacking angiotensin-converting enzyme havelow blood pressure, renal pathology, andreduced male fertility. Lab.
Invest.74:953–965.Freedman, N. J., et al. 1995. Phosphorylation and desensitization of the humanbeta 1-adrenergic receptor. Involvementof G protein-coupled receptor kinasesand cAMP-dependent protein kinase. J.Biol. Chem. 270:17 953–17 961.Koch, W. J., et al. 1995.
Cardiac functionin mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor. Science 268:1350–1353.Harding, V. B., Jones, L. R., Lefkowitz,R. J., Koch, W. J., Rockman, H. A. 2001.Cardiac beta ARK1 inhibition prolongs20.5 References64656667686970717273survival and augments beta blocker therapy in a mouse model of severe heartfailure. Proc. Natl. Acad. Sci. USA98:5809–5814.Li, Y., Love, M. L., Putkey, J. A., Cohen,C. 2000. Bepridil opens the regulatory Nterminal lobe of cardiac troponin C.
Proc.Natl. Acad. Sci. USA 97:5140–5145.Rayment, I., Holden, H. M., Sellers,J. R., Fananapazir, L., Epstein, N. D.1995. Structural interpretation of the mutations in the beta-cardiac myosin thathave been implicated in familial hypertrophic cardiomyopathy. Proc. Natl. Acad.Sci. USA 92:3864–3868.Deivanayagam, C. C., Carson, M., Thotakura, A., Narayana, S. V., Chodavarapu, R. S. 2000. Structure of FKBP12.6 incomplex with rapamycin.
Acta. Crystallogr.D. Biol. Crystallogr. 56 (Pt 3):266–271.Morais Cabral, J. H., et al. 1998. Crystalstructure and functional analysis of theHERG potassium channel N terminus: aeukaryotic PAS domain. Cell. 95:649–655.Hayakawa, K., et al. 1994. Crystallizationof canine cardiac calsequestrin. J. Mol.Biol. 235:357–360.Tomizaki, T., et al. 1999. Structure analysis of bovine heart cytochrome c oxidaseat 2.8 A resolution. Acta. Crystallogr. D.Biol. Crystallogr. 55 (Pt 1):31–45.Taylor, P., Bilsland, M., Walkinshaw,M. D. 2001. A new conformation of theintegrin-binding fragment of humanVCAM-1 crystallizes in a highly hydratedpacking arrangement. Acta. Crystallogr.
D.Biol. Crystallogr. 57:1579–1583.Janosik, M., et al. 2001. Crystallizationand preliminary X-ray diffraction analysisof the active core of human recombinantcystathionine beta-synthase: an enzymeinvolved in vascular disease. Acta. Crystallogr. D. Biol. Crystallogr. 57:289–291.van den, A. F., et al.
2000. Structure ofthe dimerized hormone-binding domainof a guanylyl-cyclase-coupled receptor.Nature 406:101–104.Casasnovas, J. M., Stehle, T., Liu, J. H.,Wang, J. H., Springer, T. A. 1998. A dimeric crystal structure for the N-terminaltwo domains of intercellular adhesionmolecule-1. Proc. Natl. Acad. Sci. USA95:4134–4139.7475767778798081828384Wiesmann, C., et al.
1997. Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor.Cell. 91:695–704.Istvan, E. S., Deisenhofer, J. 2001.Structural mechanism for statin inhibition of HMG-CoA reductase. Science292:1160–1164.Langer-Safer, P. R., et al. 1991. Replacement of finger and growth factor domains of tissue plasminogen activatorwith plasminogen kringle 1. Biochemicaland pharmacological characterization ofa novel chimera containing a high affinity fibrin-binding domain linked to a heterologous protein.
J. Biol. Chem.266:3715–3723.Keyt, B. A., et al. 1994. A faster-actingand more potent form of tissue plasminogen activator. Proc. Natl. Acad. Sci.USA 91:3670–3674.Reed, G. L., et al. 1999. A catalytic switchand the conversion of streptokinase to afibrin-targeted plasminogen activator.Proc. Natl. Acad.
Sci. USA 96:8879–8883.Hughes, R. E., et al. 2001. Altered transcription in yeast expressing expandedpolyglutamine. Proc. Natl. Acad. Sci. USA98:13 201–13 206.Plump, A. S., et al. 1992. Severe hypercholesterolemia and atherosclerosis inapolipoprotein E-deficient mice createdby homologous recombination in EScells. Cell. 71:343–353.Zhang, S. H., Reddick, R.
L., Piedrahita, J. A., Maeda, N. 1992. Spontaneoushypercholesterolemia and arterial lesionsin mice lacking apolipoprotein E. Science258:468–471.Merkel, M., Velez-Carrasco, W., Hudgins, L. C., Breslow, J. L. 2001. Compared with saturated fatty acids, dietarymonounsaturated fatty acids and carbohydrates increase atherosclerosis andVLDL cholesterol levels in LDL receptordeficient, but not apolipoprotein E-deficient, mice. Proc. Natl.
Acad. Sci. USA98:13 294–13 299.Roden, D. M., George, A. L. Jr. 2002.The genetic basis of variability in drugresponses. Nature Reviews 1:37–44.Marian, A. J. 2001. On genetics, inflammation, and abdominal aortic aneurysm:35735820 Genomics Perspective for Drug Discovery8586878889can single nucleotide polymorphismspredict the outcome? Circulation103:2222–2224.Aithal, G. P., Day, C. P., Kesteven, P. J.,Daly, A. K. 1999.
Association of polymorphisms in the cytochrome P450CYP2C9 with warfarin dose requirementand risk of bleeding complications. Lancet 353:717–719.Koytchev, R., et al. 1998. Influence ofthe cytochrome P4502D6*4 allele on thepharmacokinetics of controlled-releasemetoprolol. Eur. J. Clin. Pharmacol.54:469–474.Kuivenhoven, J. A., et al. 1998. The roleof a common variant of the cholesterylester transfer protein gene in the progression of coronary atherosclerosis.
TheRegression Growth Evaluation StatinStudy Group. N. Engl. J. Med. 338:86–93.Ueda, S., Meredith, P. A., Morton, J. J.,Connell, J. M., Elliott, H. L. 1998. ACE(I/D) genotype as a predictor of the magnitude and duration of the response toan ACE inhibitor drug (enalaprilat) inhumans. Circulation 98:2148–2153.Mitcheson, J. S., Chen, J., Lin, M., Culberson, C., Sanguinetti, M. C. 2000. Astructural basis for drug-induced long9091929394QT syndrome.