Van Eyk, Dunn - Proteomic and Genomic Analysis of Cardiovascular Disease - 2003 (522919), страница 84
Текст из файла (страница 84)
Ping, C. Song, J. Zhang, Y. Guo, X.Cao, R. C. Li, W. Wu, T. M. Vondriska,J. M. Pass, X. L. Tang, W. M. Pierce, Jr.,R. Bolli, Formation of protein kinase Ce-Lck modules confers cardioprotection.J. Clin. Invest. 2002, 109, 499–507.R. D. Edmondson, T. M. Vondriska, K. J.Biederman, J. Zhang, R. C.
Jones, Y. T.Zheng, D. L. Allen, J. X. Xiu, E. M.Cardwell, M. R. Pisano, P. Ping, Protein kinase C epsilon signaling complexes include metabolism- and transcription/translation-related proteins:complimentary electrophoretic separationtechniques with LC/MS/MS. Mol. Cell.Proteomics. 2002, 1, 421–433.J. Zhang, R. Bolli, Y. T. Zheng, J. X.Xiu, G. W. Wang, W. M. Pierce, Jr., P.30330417 Proteomic Characterization of Signaling Complexes121314151617181920Ping, Subcellular location is a major determinant of PKCe complex assembly: aview gained via functional proteomic analyses in cardioprotection.
Circulation.2001, II-209, Abstract:1005.C. P. Baines, J. Zhang, G. W. Wang, Y. T.Zheng, J. X. Xiu, E. M. Cardwell, R.Bolli, P. Ping, Mitochondrial PKCe andMAPK for signaling modules in the murine heart: enhanced mitochondrial PKCeMAPK interactions and differentialMAPK activation in PKCe-induced cardioprotection. Circ. Res. 2002, 90, 390–397.T. M. Vondriska, C.
Song, J. Zhang,X. L. Tang, X. Cao, C. P. Baines, J. M.Pass, S. Wang, R. Bolli, P. Ping, Protein kinase C e-Src modules direct signaltransduction in nitric oxide-induced cardioprotection: complex formation as ameans for cardioprotective signaling.Circ. Res. 2001, 88, 1306–1313.D. A. Berry, A. Keogh, C. G. dos Remedios, Nuclear membrane proteins in failing human dilated cardiomyopathy.
Proteomics. 2001, 1, 1507–1512.E. Braunwald, D. P. Zipes, P. Libby,Heart disease: a textbook of cardiovascular medicine. 6th Edition. W.B. SaundersCompany, Philadelphia, PA, USA, 2001.C. P. Baines, J. M. Pass, P. Ping, Proteinkinases and kinase-modulated effectors inthe late phase of ischemic preconditioning. Basic Res. Cardiol.
2001, 96, 207–218R. Bolli, The late phase of preconditioning. Circ. Res. 2000, 87, 972–983.E. C. Dempsey, A. C. Newton, D.Mochly-Rosen, A. P. Fields, M. E. Reyland, P. A. Insel, R. O. Messing, Proteinkinase C isozymes and the regulation ofdiverse cell responses. Am. J. Physiol.2000, 279, L429–L438.D. W. Dorn, 2nd, M. C. Souroujon, T.Liron, C. H. Chen, M. O. Gray, H. Z.Zhou, M. Csukai, G. Wu, J.
N. Lorenz,D. Mochly-Rosen, Sustained in vivo cardiac protection by a rationally designedpeptide that causes epsilon protein kinase C translocation. Proc. Natl. Acad. Sci.USA. 1999, 96, 12798–12803.R. C. Li, P. Ping, J. Zhang, W. B. Wead,X. Cao, J. Gao, Y. Zheng, S. Huang, J.Han, R. Bolli, PKCe modulates NFjBand AP-1 via mitogen activated kinases212223242526272829in adult rabbit cardiomyocytes. Am. J.Physiol. 1999, 279, H1679–1689.K. Ytrehus, Y.
Liu, J. M. Downey, Preconditioning protects ischemic rabbitheart by protein kinase C activation. Am.J. Physiol. 1994, 266, H1145–H1152.T. K. Seow, R. Korke, R. C. Liang, S. E.Ong, K. Ou, K. Wong, W. S. Hu, M. C.Chung, Proteomic investigation of metabolic shift in mammalian cell culture.Biotechnol. Prog. 2001, 17, 1137–1144.T.
Ideker, V. Thorsson, J. A. Ranish, R.Christmas, J. Buhler, J.K. Eng, R.Bumgarner, D. R. Goodlett, R. Aebersold, L. Hood, Integrated genomic andproteomic analyses of a systematicallyperturbed metabolic network. Science.2001, 292, 929–934.J. S. Andersen, C.
E. Lyon, A. H. Fox,A. K. Leung, Y. W. Lam, H. Steen, M.Mann, A. I. Lamond, Directed proteomicanalysis of the human nucleolus. Curr.Biol. 2002, 12, 1–11.M. Dreger, L. Bengtsson, T. Schoneberg, H. Otto, F. Hucho, Nuclear envelope proteomics: novel integral membrane proteins of the inner nuclearmembrane. Proc. Natl. Acad. Sci. USA.2001, 98, 11943–11948.A.
W. Bell, M. A. Ward, W. P. Blackstock, H. N. Freeman, J. S. Choudhary,A. P. Lewis, D. Chotai, A. Fazel, J. N.Gushue, J. Paiement, S. Palcy, E. Chevet, M. Lafreniere-Roula, R. Solari,D. Y. Thomas, A. Rowley, J. J. Bergeron,Proteomics characterization of abundantGolgi membrane proteins. J. Biol. Chem.2001, 276, 5152–5165.A. Greco, W.
Bienvenut, J. C. Sanchez,K. Kindbeiter, D. Hochstrasser, J. J.Madjar, J. J. Diaz, Identification of ribosome-associated viral and cellular basicproteins during the course of infectionwith herpes simplex virus type 1. Proteomics. 2001, 1, 545–549.D. J. Maltman, W. J. Simon, C. H.Wheeler, M. J. Dunn, R. Wait, A. R.Slabas. Proteomic analysis of the endoplasmic reticulum from developing andgerminating seed of castor (Ricinus communis). Electrophoresis 2002, 23, 626–639.J.
Predic, V. Soskic, D. Bradley, J. Godovac-Zimmermann, Monitoring of gene17.5 References3031323334353637383940expression by functional proteomics: response of human lung fibroblast cells tostimulation by endothelin-1.Biochemistry.2002, 41, 1070–1078.C. E. Murry, R. B. Jennings, K. A. Reimer, Preconditioning with ischemia: a delayof lethal cell injury in ischemic myocardium. Circulation. 1986, 74, 1124–1136.J.
M. Pass, Y. Zheng, W. B. Wead, J.Zhang, R. C. Li, R. Bolli, P. Ping,PKCe activation induces dichotomouscardiac phenotypes and modulates PKCeRACK interactions and RACK expression. Am. J. Physiol. 2001, 280, H946–H955.T. M. Vondriska, J. B. Klein, P. Ping,Use of functional proteomics to investigate PKCe-mediated cardioprotection: thesignaling module hypothesis. Am. J.Physiol. 2001, 280, H1434–H1441.J.
M. Pass, J. Zhang, T. M. Vondriska,P. Ping, Functional proteomic analysisof the PKC signaling system. In ProteinKinase C Protocols (Newton, A.C., ed.),Humana, Totowa, NJ, USA, 2002.S. M. Hanash, Biomedical applicationsof two-dimensional electrophoresis usingimmobilized pH gradients: current status. Electrophoresis. 2000, 21, 1202–1209.S. P. Gygi, R. Aebersold, Mass spectrometry and proteomics. Curr. Opin. Chem.Biol. 2000, 4, 489–494.A.
Pandey, M. Mann, Proteomics tostudy genes and genomes. Nature. 2000,405, 837–846.J. Peng, S. P. Gygi, Proteomics: themove to mixtures. J. Mass Spectrom.2001, 36, 1083–1091.A. J. Link, J. Eng, D. M. Schieltz, E.Carmack, G. J. Mize, D.
R. Morris, B. M.Garvik, J. R. Yates, 3rd, Direct analysisof protein complexes using mass spectrometry. Nat. Biotechnol. 1999, 17, 676–682.M. F. Lopez, K. Berggren, E. Chernokalskaya, A. Lazarev, M. Robinson,W. F. Patton, A comparison of silverstain and SYPRO Ruby Protein Gel Stainwith respect to protein detection in twodimensional gels and identification bypeptide mass profiling. Electrophoresis.2000, 21, 3673–3683.T. S. Lewis, J.
B. Hunt, L. D. Aveline,K. R. Jonscher, D. F. Louie, J. M. Yeh,414243444546474849T. S. Nahreini, K. A. Resing, N. G. Ahn,Identification of novel MAP kinase pathway signaling targets by functional proteomics and mass spectrometry. Mol.Cell. 2000, 6, 1343–1354.J. Madoz-Gurpide, H. Wang, D.
E. Misek, F. Brichory, S. M. Hanash, Proteinbased microarrays: a tool for probing theproteome of cancer cells and tissues. Proteomics. 2001, 1, 1279–1287.C. P. Paweletz, L. Charboneau, V. E.Bichsel, N. L. Simone, T. Chen, J. W.Gillespie, M. R. Emmert-Buck, M.
J.Roth, E. F. Petricoin, III., L. A. Liotta,Reverse phase protein microarrays whichcapture disease progression show activation of pro-survival pathways at the cancer invasion front. Oncogene. 2001, 20,1981–1989.S. C. Armstrong, C. E. Ganote, Preconditioning of isolated rabbits cardiomyoctes: effects of glycolytic blockade,phorbol esters, and ischemia. Cardiovasc.Res. 1994, 28, 1700–1706.H.
R. Cross, E. Murphy, R. Bolli, P.Ping, C. Steenbergen, Expression of activated PKCe protects the ischemic heart,without attenuating ischemic H+ production. J. Mol. Cell. Cardiol. 2002, 34, 361–367.R. B. Jennings, L. Sebbag, L. M.Schwartz, M. S. Crago, K. A. Reimer,Metabolism of preconditioned myocardium: effect of loss and reinstatement ofcardioprotection.
J. Mol. Cell. Cardiol.2001, 33, 1571–1588.K. Yabe, K. Tanonaka, M. Koshimizu, T.Katsuno, S. Takeo, A role for PKC inthe improvement of energy metabolismin preconditioned heart. Basic Res. Cardiol. 2000, 95, 215–227.A. Rizvi, X. L. Tang, Y. Qiu, Y. T. Xuan,H. Takano, A. K. Jadoon, R. Bolli, Increased protein synthesis is necessary forthe development of late preconditioningagainst myocardial stunning. Am.
J. Physiol. 1999, 277, H874–H884.H. Sasaki, N. Galang, N. Maulik, Redox regulations of NF-jB and AP-1 inischemic reperfused heart. Antioxid. Redox. Signal. 1999, 1, 317–324.Y. T. Xuan, X. L. Tang, S. Banerjee,H. Takano, R. C. Li, H. Han, Y. Qiu,30530617 Proteomic Characterization of Signaling ComplexesR. Bolli, Nuclear factor-jB plays an essential role in the late phase of ischemicpreconditioning in conscious rabbits.Circ. Res. 1999, 84, 1095–1109.50 A. M.
Krecic, M. S. Swanson, hnRNPcomplexes: composition, structure, andfunction. Curr. Opin. Cell Biol. 1999, 11,363–371.51D. S. Schullery, J. Ostrowski, O. N. Denisenko, L. Stempka, M. Shnyreva, H.Suzuki, M. Gschwendt, K. Bomsztyk,Regulated interaction of protein kinase Cd with the heterogenous nuclear ribonucleoprotein K protein. J. Biol. Chem.1999, 274, 15101–15109.30718Identification of Secreted Oxidative Stress-inducedFactors (SOXF) and Associated Proteins:Proteomics in Vascular BiologyZheng-Gen Jin, Duan-Fang Liao, Chen Yan, and Bradford C. Berk18.1IntroductionWhile reactive oxygen species (ROS), such as H2O2, O–2, and OH–, are potentiallytoxic byproducts of mitochondrial respiration and other oxidases, ROS also haveimportant physiological functions in the vasculature including regulating cell proliferation and vascular tone [1–4].
Within the vessel wall, ROS are generated byseveral mechanisms, including a vascular NAD(P)H oxidase [5, 6]. ROS formationcan be stimulated by mechanical stress, environmental factors, platelet-derivedgrowth factor (PDGF), angiotensin II (Ang II), and low-density lipoproteins [7-9].Because many risk factors for coronary artery disease such as hyperlipidemia, hypertension, diabetes, and smoking increase production of ROS, it has been suggested that changes in vessel redox state are a common pathway involved in thepathogenesis of atherosclerosis [1, 6, 10]. We have previously reported that ROSstimulate vascular smooth muscle cell (VSMC) growth and DNA synthesis [11].This proliferation was associated with stimulation of protein kinases, especiallythe extracellular signal-regulated kinases (ERK1/2) [4].Activation of ERK1/2 by O–2 generators such as the napthoquinolinedioneLY83583, menadione, and xanthine/xanthine oxidase was biphasic: an early peakof ERK1/2 activity was present at 5 to 10 min, whereas a delayed ERK1/2 activation appeared at 2 hour [12].
![](https://s.studizba.com/z.php?f=/templates/si/i/noavatar.png&w=100&h=100&t=1"){kind=avatar}
