Диссертация (Адаптивное значение для человека бактерий рода Lactobacillus и рода Bifidobacterium), страница 22

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22. - № 3. – C. 751755.143ПриложениеВыравнивание аминокислотных последовательностей белка глютаматдекарбоксилазыB(gadB) у штаммов Lactobacillus plantarum.L.plantarum_P-8L.plantarum_Taj-Apis362L.plantarum_ZJ316L.plantarum_DOMLaL.plantarum_JDM1L.plantarum_WCFS1L.plantarum_ST-IIIL.plantarum_90skL.plantarum_B21MAMLYGKHNHEAEEYLEPVFGAPSEQHDLPKYRLPKHSLSPREADRLVRDELLDEGNSRLMAMLYGKHNHEAEEYLEPVFGAPSEQHDLPKYRLPKHSLSPREADRLVRDELLDEGNSRLMAMLYGKHNHEAEEYLEPVFGAPSEQHDLPKYRLPKHSLSPREADRLVRDELLDEGNSRLMAMLYGKHNHEAEEYLEPVFGAPSEQHDLPKYRLPKHSLSPREADRLVRDELLDEGNSRLMAMLYGKHNHEAEEYLEPVFGAPSEQHDLPKYRLPKHSLSPREADRLVRDELLDEGNSRLMAMLYGKHNHEAEEYLEPVFGAPSEQHDLPKYRLPKHSLSPREADRLVRDELLDEGNSRLMAMLYGKHNHEAEEYLEPVFGAPSEQHDLPKYRLPKHSLSPREADRLVRDELLDEGNSRLMAMLYGKHNHEAEEYLEPVFGAPSEQHDLPKYRLPKHSLSPREADRLVRDELLDEGNSRLMAMLYGKHNHEAEEYLEPVFGAPSEQHDLPKYRLPKHSLSPREADRLVRDELLDEGNSRL************************************************************L.plantarum_P-8L.plantarum_Taj-Apis362L.plantarum_ZJ316L.plantarum_DOMLaL.plantarum_JDM1L.plantarum_WCFS1L.plantarum_ST-IIIL.plantarum_90skL.plantarum_B21NLATFCQTYMEPEAVELMKDTLAKNAIDKSEYPRTAEIENRCVNIIANLWHAPDDEHFTGNLATFCQTYMEPEAVELMKDTLAKNAIDKSEYPRTAEIENRCVYIIANLWHAPDDEHFTGNLATFCQTYMEPEAVELMKDTLAKNAIDKSEYPRTAEIENRCVNIIANLWHAPDDEHFTGNLATFCQTYMEPEAVELMKDTLAKNAIDKSEYPRTAEIENRCVNIIANLWHAPDDEHFTGNLATFCQTYMEPEAVELMKDTLAKNAIDKSEYPRTAEIENRCVNIIANLWHAPDDEHFTGNLATFCQTYMEPEAVELMKDTLAKNAIDKSEYPRTAEIENRCVNIIANLWHAPDDEHFTGNLATFCQTYMEPEAVELMKDTLAKNAIDKSEYPRTAEIENRCVNIIANLWHAPDDEHFTGNLATFCQTYMEPEAVELMKDTLAKNAIDKSEYPRTAEIENRCVNIIANLWHAPDDEHFTGNLATFCQTYMEPEAVELMKDTLAKNAIDKSEYPRTAEIENRCVNIIANLWHAPDDEHFTG******************************************* ****************L.plantarum_P-8L.plantarum_Taj-Apis362L.plantarum_ZJ316L.plantarum_DOMLaL.plantarum_JDM1L.plantarum_WCFS1L.plantarum_ST-IIIL.plantarum_90skL.plantarum_B21TSTIGSSEACMLGGLAMKFAWRKRAQAAGLDLNAHRPNLVISAGYQACWEKFCVYWDVDMTSTIGSSEACMLGGLAMKFAWRKRAQAAGLDLNAHRPNLVISAGYQVCWEKFCIYWDVDMTSTIGSSEACMLGGLAMKFAWRKRAQAAGLDLNAHRPNLVISAGYQVCWEKFCVYWDVDITSTIGSSEACMLGGLAMKFAWRKRAQAAGLDLNAHRPNLVISAGYQVCWEKFCVYWDVDMTSTIGSSEACMLGGLAMKFAWRKRAQAAGLDLNAHRPNLVISAGYQVCWEKFCVYWDVDMTSTIGSSEACMLGGLAMKFAWRKRAQAAGLDLNAHRPNLVISAGYQVCWEKFCVYWDVDMTSTIGSSEACMLGGLAMKFAWRKRAQAAGLDLNAHRPNLVISAGYQVCWEKFCVYWDVDMTSTIGSSEACMLGGLAMKFAWRKRAQAAGLDLNAHRPNLVISAGYQVCWEKFCVYWDVDMTSTIGSSEACMLGGLAMKFAWRKRAQAAGLDLNAHRPNLVISAGYQVCWEKFCVYWDVDM**********************************************.******:*****:L.plantarum_P-8L.plantarum_Taj-Apis362L.plantarum_ZJ316L.plantarum_DOMLaL.plantarum_JDM1L.plantarum_WCFS1L.plantarum_ST-IIIL.plantarum_90skL.plantarum_B21HMVPMDEQHMALDVDHVLNYVDEYTIGIVGIMGITYTGQYDDLAALDKVVTHYNRQHSKLHVVPMDEQHMALDVNHVLDYVDEYTIGIVGIMGITYTGQHDDLAALDKVVTHYNHQHPKLHVVPMDEQHMALDVNHVLDYVDEYTIGIVGIMGITYTGQYDDLAALDKVVTHYNHQHPKLHVVPMDEQHMALDVNHVLDYVDEYTIGIVGIMGITYTGQDDDLAALDKVVTHYNHQHPKLHVVPMDEQHMALDVNHVLDYVDEYTIGIVGIMGITYTGQDDDLAALDKVVTHYNHQHPKLHVVPMDEQHMALDVNHVLDYVDEYTIGIVGIMGITYTGQYDDLAALDKVVTHYNHQHPKLHVVPMDEQHMVLDVNHVLDYVDEYTIGIVGIMGITYTGQYDDLAALDKVVTHYNHQHPKLHVVPMDEQHMALDVNHVLDYVDEYTIGIVGIMGITYTGQYDDLAALDKVVTHYNHQHPKLHVVPMDEQHMALDVNHVLDYVDEYTIGIVGIMGITYTGQYDDLAALDKVVTHYNHQHPKL*:********.***:***:******************** **************:** **L.plantarum_P-8L.plantarum_Taj-Apis362L.plantarum_ZJ316L.plantarum_DOMLaL.plantarum_JDM1L.plantarum_WCFS1L.plantarum_ST-IIIL.plantarum_90skL.plantarum_B21PVYIHVDAASGGFYTPFIEPQLIWDFRLANVVSINASGHKYGLVYPGVGWVVWRDRQFLPPVYIHVDAASGGFYTPFIEPQLIWDFRLANVVSINASGHKYGLVYPGVGWVVWRDRQFLPPVYIHVDAASGGFYTPFIEPQLIWDFRLANVVSINASGHKYGLVYPGVGWVVWRDRQFLPPVYIHVDAASGGFYTPFIEPQLIWDFRLANVVSINASGHKYGLVYPGVGWVVWRDRQFLPPVYIHVDAASGGFYTPFIEPQLIWDFRLANVVSINASGHKYGLVYPGVGWVVWRDRQFLPPVYIHVDAASGGFYTPFIEPQLIWDFRLANVVSINASGHKYGLVYPGVGWVVWRDRQFLPPVYIHVDAASGGFYTPFIEPQLIWDFRLANVVSINASGHKYGLVYPGVGWVVWRDRQFLPPVYIHVDAASGGFYTPFIEPQLIWDFRLANVVSINASGHKYGLVYPGVGWVVWRDRQFLPPVYIHVDAASGGFYTPFIEPQLIWDFRLANVVSINASGHKYGLVYPGVGWVVWRDRQFLP************************************************************L.plantarum_P-8L.plantarum_Taj-Apis362L.plantarum_ZJ316L.plantarum_DOMLaL.plantarum_JDM1L.plantarum_WCFS1L.plantarum_ST-IIIL.plantarum_90skL.plantarum_B21PELVFKVSYLGGELPTMVINFSHSAAQLIGQYYNFIRFGMDGYREIQTKTHDVARYLAAAPELVFKVSYLGGELPTMAINFSHSAAQLIGQYYNFIRFGMDGYREIQTKTHDVARYLAAAPELVFKVSYLGGELPTMAINFSHSAAQLIGQYYNFIRFGMDGYREIQTKTHDVARYLAAAPELVFKVSYLGGELPTMAINFSHSAAQLIGQYYNFIRFGMDGYREIQTKTHDVARYLAAAPELVFKVSYLGGELPTMAINFSHSAAQLIGQYYNFIRFGMDGYREIQTKTHDVARYLAAAPELVFKVSYLGGELPTMAINFSHSAAQLIGQYYNFIRFGMDGYREIQTKTHDVARYLAAAPELVFKVSYLGGELPTMAINFSHSAAQLIGQYYNFIRFGMDGYREIQTKTHDVARYLAAAPELVFKVSYLGGELPTMAINFSHSAAQLIGQYYNFIRFGMGGYREIQTKTHDVARYLAAAPELVFKVSYLGGELPTMAINFSHSAAQLIGQYYNFIRFGMDGYREIQTKTHDVARYLAAA*****************.********************** *******************144L.plantarum_P-8L.plantarum_Taj-Apis362L.plantarum_ZJ316L.plantarum_DOMLaL.plantarum_JDM1L.plantarum_WCFS1L.plantarum_ST-IIIL.plantarum_90skL.plantarum_B21LDKVGEFKMINNGHQLPLIYYQLAPREDREWTLYDLSDRLLMNGWQVPTYPLPANLEQQVLDKVGEFKMINNGHQLPLICYQLAPREDREWTLYDLSDRLLMNGWQVPTYPLPANLEQQVLDKVGEFKMINNGHQLPLICYQLAPREDREWTLYDLSDRLLMNGWQVPTYPLPANLEQQVLDKVGEFKMINNGHQLPLICYQLAPREDREWTLYDLSDRLLMNGWQVPTYPLPANLEQQVLDKVGEFKMINNGHQLPLICYQLAPREDREWTLYDLSDRLLMNGWQVPTYPLPANLEQQVLDKVGEFKMINNGHQLPLICYQLASREDREWTLYDLSDRLLMNGWQVPTYPLPANLEQQVLDKVGEFKMINNGHQLPLICYQLAPREDREWTLYDLSDRLLMNGWQVPTYPLPANLEQQVLDKVGEFKMINNGHQLPLICYQLAPREDREWTLYDLSDRLLMNGWQVPTYPLPANLEQQVLDKVGEFKMINNGHQLPLICYQLAPREDREWTLYDLSDRLLMNGWQVPTYPLPANLEQQV******************* **** ***********************************L.plantarum_P-8L.plantarum_Taj-Apis362L.plantarum_ZJ316L.plantarum_DOMLaL.plantarum_JDM1L.plantarum_WCFS1L.plantarum_ST-IIIL.plantarum_90skL.plantarum_B21IQRIVVRADFGMNMAHDFMDDLTKAVHDLNQAHIVYHHDAAPKKYGFTH*IQRIVVRADFGVNMAHDFMDDLTEAVHDLNHAHIVYHHDAAPKKYGFTH*IQRIVVRADFGMNMAHDFMDDLTKAVHDLNQAHIVYHHDAAPKKYGFTH*IQRIVVRADFGMNMAHDFMDDLTKAVHDLNHAHIVYHHDAAPKKYGFTH*IQRIVVRADFGMNMAHDFMDDLTKAVHDLNHAHIVYHHDAAPKKYGFTH*IQRIVVRADFGMNMAHDFMDDLTKAVHDLNHAHIVYHHDAAPKKYGFTH*IQRIVVRADFGMNMAHDFMDDLTKAVHDLNHAHIVYHHDAAPKKYGFTH*IQRIVVRADFGMNMAHDFMDDLTKAVHDLNHAHIVYHHDAAPKKYGFTH*IQRIVVRADFGMNMAHDFMDDLTKAVHDLNHAHIVYHHDAAPKKYGFTH************:***********:******:*******************Выравнивание аминокислотных последовательностей белка антипортера (gadC) уштаммов Lactobacillus plantarum.L.plantarum_P-8L.plantarum_16L.plantarum_90skL.plantarum_WCFS1L.plantarum_B21L.plantarum_DOMLaL.plantarum_JDM1L.plantarum_ST-MENKKQLRWSNIALIAFVAVWGLGNVVNNFALQGLSVVTSWILIMIIYFIPYTLIVGQLGMENKKQLRWSNIALIAFVAVWGLGNVVNNFALQGLSVVTSWILIMIIYFIPYTLIVGQLGMANEKQLRWSNIALIAFVAVWGLGNVVNNFALQGLSVVTSWILIMIIYFIPYTLIVGQLGMANEKQLRWSNIALIAFVAVWGLGNVVNNFALQGLSVVTSWILIMIIYFIPYTLIVGQLGMENEKQLRWSNIALIAFVAVWGLGNVVNNFALQGLSVVTSWILIMIIYFIPYTLIVGQLGMENEKQLRWSNIALIAFVAVWGLGNVVNNFALQGLSVVTSWILIMIIYFIPYTLIVGQLGMENEKQLRWSNIALIAFVAVWGLGNVVNNFALQGLSVVTSWILIMIIYFIPYTLIVGQLGMENEKQLRWSNIALIAFVAVWGLGNVVNNFALQGLSVVTSWILIMIIYFIPYTLIVGQLG* *:********************************************************L.plantarum_P-8L.plantarum_16L.plantarum_90skL.plantarum_WCFS1L.plantarum_B21L.plantarum_DOMLaL.plantarum_JDM1L.plantarum_ST-STFKDAEGGVSSWIRATSTKRLAYYAAWTYWIVHIPYLAQKPQGILIAFSWLFRGNGNFVSTFKDAEGGVSSWIRATSTKRLAYYAAWTYWIVHIPYLAQKPQGILIAFSWLFRGNGNFVSTFKDAEGGVSSWIRATSTKRLAYYAAWTYWIVHIPYLAQKPQGILIAFSWLFRGNGNFVSTFKDAEGGVSSWIRATSTKRLAYYAAWTYWIVHIPYLAQKPQGILIAFSWLFRGNGNFVSTFKDAEGGVSSWIRATSTKRLAYYAAWTYWIVHIPYLAQKPQGILIAFSWLFRGNGNFVSTFKDAEGGVSSWIRATSTKRLAYYAAWTYWIVHIPYLAQKPQGILIAFSWLFRGNGNFVSTFKDAEGGVSSWIRATSTKRLAYYAAWTYWIVHIPYLAQKPQGILIAFSWLFRGNGNFVSTFKDAEGGVSSWIRATSTKRLAYYAAWTYWIVHIPYLAQKPQGILIAFSWLFRGNGNFV************************************************************L.plantarum_P-8L.plantarum_16L.plantarum_90skL.plantarum_WCFS1L.plantarum_B21L.plantarum_DOMLaL.plantarum_JDM1L.plantarum_ST-NTTPALVVQAICLVLFLFFLWIASLGLTTLKRIGSVAGTGMFIMSILFIILAVSAPFMTKNTTPALVVQAICLVLFLFFLWIASLGLTTLKRIGSVAGTGMFIMSILFIILAVSAPFMTKNTTPALVVQAICLVLFLFFLWIASLGLTTLKRIGSVAGTGMFIMSILFIILAVSAPFMTKNTTPALVVQAICLVLFLFFLWIASLGLTTLKRIGSVAGTGMFIMSILFIILAVSAPFMTKNTTPALVVQAICLVLFLFFLWIASLGLTTLKRIGSVAGTGMFIMSILFIILAVSAPFMTKNTTPALVVQAICLVLFLFFLWIASLGLTTLKRIGSVAGTGMFIMSILFIILAVSAPFMTKNTTPALVVQAICLVLFLFFLWIASLGLTTLKRIGSVAGTGMFIMSILFIILAVSAPFMTKNTTPALVVQAICLVLFLFFLWIASLGLTTLKRIGSVAGTGMFIMSILFIILAVSAPFMTK************************************************************L.plantarum_P-8L.plantarum_16L.plantarum_90skL.plantarum_WCFS1L.plantarum_B21L.plantarum_DOMLaL.plantarum_JDM1L.plantarum_ST-ATVQTPNMFSLKSYLPKFDFTYFTTVSMLVFAVGGSEKISPYVNKTKNPGREFPLGMLVLATVQTPNMFSLKSYLPKFDFTYFTTVSMLVFAVGGSEKISPYVNKTKNPGREFPLGMLVLATVQTPNMFSLKSYLPKFDFTYFTTVSMLVFAVGGSEKISPYVNKTKNPGREFPLGMLVLATVQTPNMFSLKSYLPKFDFTYFTTVSMLVFAVGGSEKISPYVNKTKNPGREFPLGMLVLATVQTPNMFSLKSYLPKFDFTYFTTVSMLVFAVGGSEKISPYVNKTKNPGREFPLGMLVLATVQTPNMFSLKSYLPKFDFTYFTTVSMLVFAVGGSEKISPYVNKTKNPGREFPLGMLVLATVQTPNMFSLKSYLPKFDFTYFTTVSMLVFAVGGSEKISPYVNKTKNPGREFPLGMLVLATVQTPNMFSLKSYLPKFDFTYFTTVSMLVFAVGGSEKISPYVNKTKNPGREFPLGMLVL************************************************************145L.plantarum_P-8L.plantarum_16L.plantarum_90skL.plantarum_WCFS1L.plantarum_B21L.plantarum_DOMLaL.plantarum_JDM1L.plantarum_ST-AGMVAICALLGSFAMGILFNSKHIPADLMANGAYYAFQRLGAFYHVGNLFLILYAIANVLAGMVAICALLGSFAMGILFNSKHIPADLMANGAYYAFQRLGAFYHVGNLFLILYAIANVLAGMVAICALLGSFAMGILFNSKHIPADLMANGAYYAFQRLGAFYHVGNLFLILYAIANVLAGMVAICALLGSFAMGILFNSKHIPADLMANGAYYAFQRLGAFYHVGNLFLILYAIANVLAGMVAICALLGSFAMGILFNSKHIPADLMANGAYYAFQRLGAFYHVGNLFLILYAIANVLAGMVAICALLGSFAMGILFNSKHIPADLMANGAYYAFQRLGAFYHVGNLFLILYAIANVLAGMVAICALLGSFAMGILFNSKHIPADLMANGAYYAFQRLGAFYHVGNLFLILYAIANVLAGMVAICALLGSFAMGILFNSKHIPADLMANGAYYAFQRLGAFYHVGNLFLILYAIANVL************************************************************L.plantarum_P-8L.plantarum_16L.plantarum_90skL.plantarum_WCFS1L.plantarum_B21L.plantarum_DOMLaL.plantarum_JDM1L.plantarum_ST-AQISALAFSIDAPLKILLGDADPEFIPKKLSKMNKKDVPVNGYILTGVLVSILIIIPALGAQISALAFSIDAPLKILLGDADPEFIPKKLSKMNKKDVPVNGYILTGVLVSILIIIPALGAQISALAFSIDAPLKILLGDADPEFIPKKLSKMNKKDVPVNGYILTGVLVSILIIIPALGAQISALAFSIDAPLKILLGDADPEFIPKKLSKMNKKDVPVNGYILTGVLVSILIIIPALGAQISALAFSIDAPLKILLGDADPEFIPKKLSKMNKKDVPVNGYILTGVLVSILIIIPALGAQISALAFSIDAPLKILLGDADPEFIPKKLSKMNKKDVPVNGYILTGVLVSILIIIPALGAQISALAFSIDAPLKILLGDADPEFIPKKLSKMNKKDVPVNGYILTGVLVSILIIIPALGAQISALAFSIDAPLKILLGDADPEFIPKKLSKMNKKDVPVNGYILTGVLVSILIIIPALG************************************************************L.plantarum_P-8L.plantarum_16L.plantarum_90skL.plantarum_WCFS1L.plantarum_B21L.plantarum_DOMLaL.plantarum_JDM1L.plantarum_ST-IGNMNELFNWLLNLNSVVMPMRYLWVFLAYMLLNKHLKEFKSDYKFLKNPVAGRLVGAWCIGNMNELFNWLLNLNSVVMPMRYLWVFLAYMLLNKHLKEFKSDYKFLKNPVAGRLVGAWCIGNMNELFNWLLNLNSVVMPMRYLWVFLAYMLLNKHLKEFKSDYKFLKNPVAGRLVGAWCIGNMNELFNWLLNLNSVVMPMRYLWVFLAYMLLNKHLKEFKSDYKFLKNPVAGRLVGAWCIGNMNELFNWLLNLNSVVMPMRYLWVFLAYMLLNKHLKEFKSDYKFLKNPVAGRLVGAWCIGNMNELFNWLLNLNSVVMPMRYLWVFLAYMLLNKHLKEFKSDYKFLKNPVAGRLVGAWCIGNMNELFNWLLNLNSVVMPMRYLWVFLAYMLLNKHLKEFKSDYKFLKNPVAGRLVGAWCIGNMNELFNWLLNLNSVVMPMRYLWVFLAYMLLNKHLKEFKSDYKFLKNPVAGRLVGAWC************************************************************L.plantarum_P-8L.plantarum_16L.plantarum_90skL.plantarum_WCFS1L.plantarum_B21L.plantarum_DOMLaL.plantarum_JDM1L.plantarum_ST-FLFTAFACILGMVPKTSYASNPSSWLFQLTLNILTPIIFVALGMILPMIARRHRTKTA*FLFTAFACILGMVPKTSYASNPSSWLFQLTLNILTPIIFVALGMILPMIARRHRTKTA*FLFTAFACILGMVPKTSYASNPSSWLFQLTLNILTPIIFVALGMILPMIARRHRTKTA*FLFTAFACILGMVPKTSYASNPSSWLFQLTLNILTPIIFVALGMILPMIARRHRTKTA*FLFTAFACILGMVPKTSYASNPSSWLFQLTLNILTPIIFVALGMILPMIARRHRTKTA*FLFTAFACILGMVPKTSYASNPSSWLFQLTLNILTPIIFVALGMILPMIARRHRTKTA*FLFTAFACILGMVPKTSYASNPSSWLFQLTLNILTPIIFVALGMILPMIARRHRTKTA*FLFTAFACILGMVPKTSYASNPSSWLFQLTLNILTPIIFVALGMILPMIARRHRTKTA************************************************************Выравнивание аминокислотных последовательностей белка антипортера (gadC) уштаммов Lactobacillus brevis.L.brevis_15fL.brevis_KB290L.brevis_BSOL.brevis_CGMCCL.brevis_ATCCVDENKSGQQIDTQKANRITGFQLFSMTTSMVMTVYGFAAFAKQGPTAFFYLFLAGILWFLVDENKSEQQIDTQKANRITGFQLFSMTTSMVMTVYGFAAFAKQGPTAFFYLFLAGILWFLVDENKSEQQIDTQKANRITGFQLFSMTTSMVMTVYGFAAFAKQGPTAFFYLFLAGILWFLVDENKSEQQIDTQKANRITGFQLFSMTTSMVMTVYGFAAFAKQGPTAFFYLFLAGILWFLVDENKSEQQIDTQKANRITGFQLFSMTTSMVMTVYGFAAFAKQGPTAFFYLFLAGILWFL****** *****************************************************L.brevis_15fL.brevis_KB290L.brevis_BSOL.brevis_CGMCCL.brevis_ATCCPVTRTSGEMASIDGWSKGGIFTWSRNMLGERAGWSALFYQWIHITVGMNTMMYFIIGCFSPVTRTSGEMASIDGWSKGGIFTWSRNMLGERAGWSALFYQWIHITVGMNTMMYFIIGCFSPVTRTSGEMASIDGWSKGGIFTWSRNMLGERAGWSALFYQWIHITVGMNTMMYFIIGCFSPVTRTSGEMASIDGWSKGGIFTWSRNMLGERAGWSALFYQWIHITVGMNTMMYFIIGCFSPVTRTSGEMASIDGWSKGGIFTWSRNMLGERAGWSALFYQWIHITVGMNTMMYFIIGCFS************************************************************L.brevis_15fL.brevis_KB290L.brevis_BSOL.brevis_CGMCCL.brevis_ATCCVTFGLPIITDNPLVKFILMMVILWGLIFLQQKGTSVTGKIAQWCFTLGVIIPVFFLLFLFVTFGLPIITDNPLVKFILMMIILWGLIFLQQKGTSVTGKIAQWCFTLGVIIPVFFLLFLFVTFGLPIITDNPLVKFILMMIILWGLIFLQQKGTSVTGKIAQWCFTLGVITPVFFLLFLFVTFGLPIITDNPLVKFILMMIILWGLIFLQQKGTSVTGKIAQWCFTLGVIIPVFFLLFLFVTFGLPIITDNPLVKFILMMIILWGLIFLQQKGTSVTGKIAQWCFTLGVIIPVFFLLFLF********************:***************************** *********146L.brevis_15fL.brevis_KB290L.brevis_BSOL.brevis_CGMCCL.brevis_ATCCILYLVQGNPAMIHVNMHTIFPSSWNGSVLVGFVPFILAFAGAEGSAPHVKDLDKPSIYPKILYLVQGNPAMIHVNMHTIFPSSWNGSVLVGFVPFILAFAGAEGSAPHVKDLDKPSIYPKILYLVQGNPAMIHVNMHTIFPSSWNGSVLVGFVPFILAFAGAEGSAPHVKDLDKPSIYPKILYLVQGNPAMIHVNMHTIFPSSWNGSVLVGFVPFILAFAGAEGSAPHVKDLDKPSIYPKILYLVQGNPAMIHVNMHTIFPSSWNGSVLVGFVPFILAFAGAEGSAPHVKDLDKPSIYPK************************************************************L.brevis_15fL.brevis_KB290L.brevis_BSOL.brevis_CGMCCL.brevis_ATCCVMMALAIAAICSDIIGSMAIAMTIPSNQIQLSNGIVYAYGALVARYGVSVIFVEKLTGFLVMMALAVAAICSDIIGSMAIAMTIPNNQIQLSNGIVYAYGALVARYGVGVVFVEKLTGFLVMMALAVAAICSDIIGSMAIAMTIPNNQIQLSNGIVYAYGALVARYGVGVVFVEKLTGFLVMMALAVAAICSDIIGSMAIAMTIPNNQIQLSNGIVYAYGALVARYGVGVVFVEKLTGFLVMMALAVAAICSDIIGSMAIAMTIPNNQIQLSNGIVYAYGALVARYGVGVVFVEKLTGFL******:******************.**********************.*:*********L.brevis_15fL.brevis_KB290L.brevis_BSOL.brevis_CGMCCL.brevis_ATCCLAVGVLGEISSWVVGPNAGMFEAAKAGYLPPRFSKANKYGIETNVMVLQGVIVSIVGALLLAVGVLGEISSWVVGPNAGMFEAAKAGYLPPRFSKANKYGIEINVMVLQGVIVSIVGALLLAVGVLGEISSWVVGPNAGMFEAAKAGYLPPRFSKANKYGIETNVMVLQGVIVSIVGALLLAVGVLGEISSWVVGPNAGMFEAAKAGYLPPRFSKANKYGIETNVMVLQGVIVSIVGALLLAVGVLGEISSWVVGPNAGMFEAAKAGYLPPRFSKANKYGIETNVMVLQGVIVSIVGALL****************************************** *****************L.brevis_15fL.brevis_KB290L.brevis_BSOL.brevis_CGMCCL.brevis_ATCCTFGAGGNKSSLSFQTAMSLTVALYTLMYMLMFISYLVLQFKYVDLHRDFVAAKSRWLRITTFGAGGDKASLSFQTAMSLTVALYTLMYMLMFISYLVLQFKYVDLHRDFVAAKSRWLRITTFGAGGNKASLSFQTAMSLTVALYTLMYMLMFISYLVLQFKYVDLHRDFVAAKSRWLRITTFGAGGNKASLSFQTAMSLTVALYTLMYMLMFISYLVLQFKYVDLHRDFVAAKSRWLRITTFGAGGNKASLSFQTAMSLTVALYTLMYMLMFISYLVLQFKYVDLHRDFVAAKSRWLRIT******:*:***************************************************L.brevis_15fL.brevis_KB290L.brevis_BSOL.brevis_CGMCCL.brevis_ATCCYGILGFILSAFGFVVTFFPPADLSVASKHTYLMLLVSAFVVMLVLPFILYRFHDKWALQLYGILGFILSAFGFVVTFFPPADLSVASKHTYLMLLVSAFVVMLVLPFILYRFHDKWALQLYGILGFILSAFGFVVTFFPPADLSVASKHTYLMLLVSAFVVMLVLPFILYRFHDKWALQLYGILGFILSAFGFVVTFFPPADLSVASKHTYLMLLVSAFVVMLVLPFILYRFHDKWALQLYGILGFILSAFGFVVTFFPPADLSVASKHTYLMLLVSAFVVMLVLPFILYRFHDKWALQL************************************************************L.brevis_15fL.brevis_KB290L.brevis_BSOL.brevis_CGMCCL.brevis_ATCCGVNVDEVAAPTGHEALEKETK*GVNVDEVAAPTGHEALEKETK*GVNVDEVAAPTGHEALEKETK*GVNVDEVAAPTGHEALEKETK*GVNVDEVAAPTGHEALEKETK***********************ВыравниваниеаминокислотныхпоследовательностейглютаматдекарбоксилазыB1 (gadB1) у штаммов Lactobacillus brevis.L.brevis_15fL.brevis_CGMCC1306L.brevis_BSOL.brevis_BH2L.brevis_ATCC367L.brevis_KB290MNKNDQETQQMINNVDLEKTFLGSVEAGQSLPTNTLPNDPMAPDVAAQLVEHYRLNEAKAMNKNDQETQQMINNVDLEKTFLGSVEAGQSLPTNTLPDDPMAPDVAAQLVEHYRLNEAKAMNKNDQETQQMINNVDLEKTFLGSVEAGQSLPTNTLPDDPMAPDVAAQLVEHYRLNEAKAMNKNDQETQQMINNVDLEKTFLGSVEAGQSLPTNTLPDDPMAPDVAAQLVEHYRLNEAKAMNKNDQETQQMINNVDLEKTFLGSVEAGQSLPTNTLPDDPMAPDVAAQLVEHYRLNEAKAMNKNDQETQQMINNVDLEKTFLGSVEAGQSLPTNTLPDDPMAPDVAAQLVEHYRLNEAKA*************************************:**********************L.brevis_15fL.brevis_CGMCC1306L.brevis_BSOL.brevis_BH2L.brevis_ATCC367L.brevis_KB290NQNLATFCTTQMEPQADELMKNALNTNAIDKSEYPKTAAMENYCVSMIAHLWGIPDNEKINQNLATFCTTQMEPQADELMKNALNTNAIDKSEYPKTAAMENYCVSMIAHLWGIPDNEKINQNLATFCTTQMEPQADELMKNALNTNAIDKSEYPKTAAMENYCVSMIAHLWGIPDNEKINQNLATFCTTQMEPQADELMKNALNTNAIDKSEYPKTAAMENYCVSMIAHLWGIPDNEKINQNLATFCTTQMEPQADELMKNALNTNAIDKSEYPKTAAMENYCVSMIAHLWGIPDNEKINQNLATFCTTQMEPQADELMKNALNTNAIDKSEYPKTAAMENYCVSMIAHLWGIPDNEKI************************************************************белка147L.brevis_15fL.brevis_CGMCC1306L.brevis_BSOL.brevis_BH2L.brevis_ATCC367L.brevis_KB290YDDFIGTSTVGSSEGCMLGGLALLHSWKHRAKAAGFDIEDLHSHKPNLVIMSGYQVVWEKYDDFIGTSTVGSSEGCMLGGLALLHSWKHRAKAAGFDIEDLHSHKPNLVIMSGYQVVWEKYDDFIGTSTVGSSEGCMLGGLALLHSWKHRAKAAGFDIEDLHSHKPNLVIMSGYQVVWEKYDDFIGTSTVGSSEGCMLGGLALLHSWKHRAKAAGFDIEDLHSHKPNLVIMSGYQVVWEKYDDFIGTSTVGSSEGCMLGGLALLHSWKHRAKAAGFDIEDLHSHKPNLVIMSGYQVVWEKYDDFIGTSTVGSSEGCMLGGLALLHSWKHRAKAAGFDIEDLHSHKPNLVIMSGYQVVWEK************************************************************L.brevis_15fL.brevis_CGMCC1306L.brevis_BSOL.brevis_BH2L.brevis_ATCC367L.brevis_KB290FCTYWNVEMRQVPINGDQVSLDMDHVMDYVDENTIGIIGIEGITYTGSVDDIQMLDNLVTFCTYWNVEMRQVPINGDQVSLDMDHVMDYVDENTIGIIGIEGITYTGSVDDIQTLDNLVTFCTYWNVEMRQVPINGDQVSLDMDHVMDYVDENTIGIIGIEGITYTGSVDDIQTLDNLVTFCTYWNVEMRQVPINGDQVSLDMDHVMDYVDENTIGIIGIEGITYTGSVDDIQTLDNLVTFCTYWNVEMRQVPINGDQVSLDMDHVMDYVDENTIGIIGIEGITYTGSVDDIQTLDNLVTFCTYWNVEMRQVPINGDQVSLDMDHVMDYVDENTIGIIGIEGITYTGSVDDIQTLDNLVT***************************************************** ******L.brevis_15fL.brevis_CGMCC1306L.brevis_BSOL.brevis_BH2L.brevis_ATCC367L.brevis_KB290EYNKTATMPVRIHVDAAFGGLFAPFVDGFNPWDFRLKNVVSINVSGHKYGMVYPGLGWIVEYNKTATMPVRIHVDAAFGGLFAPFVDGFNPWDFRLKNVVSINVSGHKYGMVYPGLGWIVEYNKTATMPVRIHVDAAFGGLFAPFVDGFNPWDFRLKNVVSINVSGHKYGMVYPGLGWIVEYNKTATMPVRIHVDAAFGGLFAPFVDGFNPWDFRLKNVVSINVSGHKYGMVYPGLGWIVEYNKTATMPVRIHVDAAFGGLFAPFVDGFNPWDFRLKNVVSINVSGHKYGMVYPGLGWIVEYNKTATMPVRIHVDAAFGGLFAPFVDGFNPWDFRLKNVVSINVSGHKYGMVYPGLGWIV************************************************************L.brevis_15fL.brevis_CGMCC1306L.brevis_BSOL.brevis_BH2L.brevis_ATCC367L.brevis_KB290WRHNTADILPAEMRFQVPYLGKTVDSIAINFSHSGAHISAQYYNFIRFGLSGYKTIMQNVWRHDTADILPAEMRFQVPYLGKTVDSIAINFSHSGAHISAQYYNFIRFGLSGYKTIMQNVWRHNTADILPAEMRFQVPYLGKTVDSIAINFSHSGAHISAQYYNFIRFGLSGYKTIMQNVWRHNTADILPAEMRFQVPYLGKTVDSIAINFSHSGAHISAQYYNFIRFGLSGYKTIMQNVWRHNTADILPAEMRFQVPYLGKTVDSIAINFSHSGAHISAQYYNFIRFGLSGYKTIMQNVWRHNTADILPAEMRFQVPYLGKTVDSIAINFSHSGAHISAQYYNFIRFGLSGYKTIMQNV***:********************************************************L.brevis_15fL.brevis_CGMCC1306L.brevis_BSOL.brevis_BH2L.brevis_ATCC367L.brevis_KB290RKVSLKLTAALKTYGIFDILVDGSQLPINCWKLADDAPVGWTLYDLKSELAKYGWQVPAYRKVSLKLTAALKTYGIFDILVDGSQLPINCWKLADDAPVGWTLYDLESELAKYGWQVPAYRKVSLKLTAALKTYGIFDILVDGSQLPINCWKLADDAPVGWTLYDLESELAKYGWQVPAYRKVSLKLTAALKTYGIFDILVDGSQLPINCWKLADDAPVGWTLYDLESELAKYGWQVPAYRKVSLKLTAALKTYGIFDILVDGSQLPINCWKLADDAPVGWTLYDLESELAKYGWQVPAYRKVSLKLTAALKTYGIFDILVDGSQLPINCWKLADDAPVGWTLYDLESELAKYGWQVPAY**********************************************:*************L.brevis_15fL.brevis_CGMCC1306L.brevis_BSOL.brevis_BH2L.brevis_ATCC367L.brevis_KB290PLPKNRDDVTISRIVVRPSMTMTIADDFLDDLKLAIDGLNHTFGVTTTVDQDNKTTVRS*PLPKNRDDVTISRIVVRPSMTMTIADDFLDDLKLAIDGLNHTFGVTTTVDQDNKTTVRS*PLPKNRDDVTISRIVVRPSMTMTIADDFLDDLKLAIDGLNHTFGVTTTVDQDNKTTVRS*PLPKNRDDVTISRIVVRPSMTMTIADDFLDDLKLAIDGLNHTFGVTTTVDQDNKTTVRS*PLPKNRDDVTISRIVVRPSMTMTIADDFLDDLKLAIDGLNHTFGVTTTVDQDNKTTVRS*PLPKNRDDVTISRIVVRPSMTMTIADDFLDDLKLAIDGLNHTFGVTTTVDQNNKTTVRS****************************************************:********148ВыравниваниеаминокислотныхпоследовательностейглютаматдекарбоксилазыB2 (gadB2) у штаммов Lactobacillus brevis.L.brevis_BH2L.brevis_BSOL.brevis_15fL.brevis_KB290L.brevis_ATCCL.brevis_CGMCCL.brevis_877GMAMLYGKHPHETDETLTPIFGATAERHDLPKYKLAKHALEPREADRLVRDQLLDEGNSRLMAMLYGKHTHETDETLTPIFGATAERHDLPKYKLAKHALEPREADRLVRDQLLDEGNSRLMAMLYGKHTHETDETLTPIFGASAERHDLPKYKLAKHALEPREADRLVRDQLLDEGNSRLMAMLYGKHTHETDETLKPIFGASAERHDLPKYKLAKHALEPREADRLVRDQLLDEGNSRLMAMLYGKHTHETDETLKPIFGASAERHDLPKYKLAKHALEPREADRLVRDQLLDEGNSRLMAMLYGKHTHETDETLKPIFGASAERHDLPKYKLAKHALEPREADRLVRDQLLDEGNSRLMAMLYGKHTHETDETLKPIFGASAERHDLPKYKLAKHALEPREADRLVRDQLSDEGNSRL******** *******.*****:***************************** *******L.brevis_BH2L.brevis_BSOL.brevis_15fL.brevis_KB290L.brevis_ATCCL.brevis_CGMCCL.brevis_877GNLATFCQTYMEPEAVELMKDTLEKNAIDKSEYPRTAEIENRCVNIIANLWHAPEAESFTGNLATFCQTYMEPEAVELMKDTLEKNAIDKSEYPRTAEIENRCVNIIANLWHAPEAESFTGNLATFCQTYMEPEAVELMKDTLEKNAIDKSEYPRTAEIENRCVNIIANLWHAPEAESFTGNLATFCQTYMEPEAVELMKDTLEKNAIDKSEYPRTAEIENRCVNIIANLWHAPEAESFTGNLATFCQTYMEPEAVELMKDTLEKNAIDKSEYPRTAEIENRCVNIIANLWHAPEAESFTGNLATFCQTYMEPEAVELMKDTLEKNAIDKSEYPRTAEIENRCVNIIANLWHAPEAESFTGNLATFCQTYMEPEAVELMKDTLEKNAIDKSEYPRTAEIENRCVNIIANLWHAPEAESFTG************************************************************L.brevis_BH2L.brevis_BSOL.brevis_15fL.brevis_KB290L.brevis_ATCCL.brevis_CGMCCL.brevis_877GTSTIGSSEACMLAGLAMKFAWRKRAKANGLDLNAHHPNIVTSAGYQVCWEKFCVYWDIDMTSTIGSSEACMLAGLAMKFAWRKRAKANGLDLTAHQPNIVISAGYQVCWEKFCVYWDIDMTSTIGSSEACMLAGLAMKFAWRKRAKANGLDLTAHQPNIVISAGYQVCWEKFCVYWDIDMTSTIGSSEACMLAGLAMKFAWRKRAKANGLDLTAHQPNIVISAGYQVCWEKFCVYWDIDMTSTIGSSEACMLAGLAMKFAWRKRAKANGLDLTAHQPNIVISAGYQVCWEKFCVYWDIDMTSTIGSSEACMLAGLAMKFAWRKRAKANGLDLTAHQPNIVISAGYQVCWEKFCVYWDIDMTSTIGSSEACMLAGLAMKFAWRKRAKANGLDLTAHQPNIVISAGYQVCWEKFCVYWDIDM********************************.**:**** *******************L.brevis_BH2L.brevis_BSOL.brevis_15fL.brevis_KB290L.brevis_ATCCL.brevis_CGMCCL.brevis_877GHVVPMDDDHMSLNVDHVLDYVDDYTIGIVGIMGITYTGQYDDLARLDAVVERYNRTTKFPHVVPMDDDHMSLNVDHVLDYVDDYTIGIVGIMGITYTGQYDDLARLDAVVERYNRTTKFPHVVPMDDDHMSLNVDHVLDYVDDYTIGIVGIMGITYTGQYDDLVRLDAVVERYNRTTKFPHVVPMDDDHMSLNVDHVLDYVDDYTIGIVGIMGITYTGQYDDLARLDAVVERYNRTTKFPHVVPMDDDHMSLNVDHVLDYVDDYTIGIVGIMGITYTGQYDDLARLDAVVERYNRTTKFPHVVPMDDDHMSLNVDHVLDYVDDYTIGIVGIMGITYTGQYDDLARLDAVVERYNRTTKFPHVVPMDDDHMSLNVDHVLDYVDDYTIGIVGIMGITYTGQYDDLARLDAVVERYNRTTKFP*******************************************.****************L.brevis_BH2L.brevis_BSOL.brevis_15fL.brevis_KB290L.brevis_ATCCL.brevis_CGMCCL.brevis_877GVYIHVDAASGGFYTPFIEPELKWDFRLNNVISINASGHKYGLVYPGVGWVIWRDQQYLPKVYIHVDAASGGFYTPFIEPELKWDFRLNNVISINASGHKYGLVYPGVGWVIWRDQQYLPKVYIHVDAASGGFYTPFIEPELKWDFRLNNVISINASGHKYGLVYPGVGWVIWRDQQYLPKVYIHVDAASGGFYTPFIEPELKWDFRLNNVISINASGHKYGLVYPGVGWVIWRDQQYLPKVYIHVDAASGGFYTPFIEPELKWDFRLNNVISINASGHKYGLVYPGVGWVIWRDQQYLPKVYIHVDAASGGFYTPFIEPELKWDFRLNNVISINASGHKYGLVYPGVGWVIWRDQQYLPKVYIHVDAASGGFYTPFIEPELKWDFRLNNVISINASGHKYGLVYPGVGWVIWRDQQYLPK************************************************************L.brevis_BH2L.brevis_BSOL.brevis_15fL.brevis_KB290L.brevis_ATCCL.brevis_CGMCCL.brevis_877GELVFKVSYLGGELPTMAINFSHSASQLIGQYYNFIRFGFDGYREIQEKTHDVARYLAKSLELVFKVSYLGGELPTMAINFSHSASQLIGQYYNFIRFGFDGYREIQEKTHDVARYLAKSLELVFKVSYLGGELPTMAINFSHSASQLIGQYYNFIRFGFDGYREIQEKTHDVARYLAKSLELVFKVSYLGGELPTMAINFSHSASQLIGQYYNFIRFGFDGYREIQEKTHDVARYLAKSLELVFKVSYLGGELPTMAINFSHSASQLIGQYYNFIRFGFDGYREIQEKTHDVARYLAKSLELVFKVSYLGGELPTMAINFSHSASQLIGQYYNFIRFGFDGYREIQEKTHDVARYLAKSLELVFKVSYLGGELPTMAINFSHSASQLIGQYYNFIRFGFDGYREIQEKTHDVARYLAKSL************************************************************L.brevis_BH2L.brevis_BSOL.brevis_15fL.brevis_KB290L.brevis_ATCCL.brevis_CGMCCL.brevis_877GTKLGGFSLINDGHELPLICYELTADSDREWTLYDLSDRLLMKGWQVPTYPLPKNMADRVITKLGGFSLINDGHELPLICYELTADSDREWTLYDLSDRLLMKGWQVPTYPLPKNMADRVITKLGGFSLINDGHELPLICYELTADSDREWTLYDLSDRLLMKGWQVPTYPLPKNMTDRVITKLGGFSLINDGHELPLICYELTADSDREWTLYDLSDRLLMKGWQVPTYPLPKNMTDRVITKLGGFSLINDGHELPLICYELTADSDREWTLYDLSDRLLMKGWQVPTYPLPKNMTDRVITKLGGFSLINDGHELPLICYELTADSDREWTLYDLSDRLLMKGWQVPTYPLPKNMTDRVITKLGGFSLINDGHELPLICYELTADSDREWTLYDLSDRLLMKGWQVPTYPLPKNMTDRVI*******************************************************:****белка149L.brevis_BH2L.brevis_BSOL.brevis_15fL.brevis_KB290L.brevis_ATCCL.brevis_CGMCCL.brevis_877GQRIVVRADFGMSMAHDFIDDLTQAIHDLDQAHIVFHSDPQPKKYGFTH*QRIVVRADFGMSMAHDFIDDLTQAIHDLDQAHIVFHSDPQPKKYGFTH*QRIVVRADFGMSMAHDFIDDLTQAIHDLDQAHIVFHSDPQPKKYGFTH*QRIVVRADFGMSMAHDFIDDLTQAIHDLDQAHIVFHSDPQPKKYGFTH*QRIVVRADFGMSMAHDFIDDLTQAIHDLDQAHIVFHSDPQPKKYGFTH*QRIVVRADFGMSMAHDFIDDLTQAIHDLDQAHIVFHSDPQPKKYGFTH*QRIVVRADFGMSMAHDFIDDLTQAIHDLDQAHIVFHSDPQPKKYGFTH**************************************************Выравнивание аминокислотных последовательностей белка глютаматдекарбоксилазыB(gadB) у штаммов Bifidobacterium angulatum.B.angulatum_GT102B.angulatum_LMGB.angulatum_DSMMSDMHFSTTASSTCCGNDTRDADRLGSVEINPLFARPKEARSFPKNRIPDTGSLPETAYQMSDTHFSTTASSTCCGNDTRDADRLGSVEINPLFARPKEARSFPKNRIPDTGSLPETAYQMSDTHFSTTASSTCCGNDTRDADRLGSVEINPLFARPKEARSFPKNRIPDTGSLPETAYQ*** ********************************************************B.angulatum_GT102B.angulatum_LMGB.angulatum_DSMVVHDDAMLDGNARLNLATFVGTWMDDYANRIYMEAADKNMIDKDEYPKTAEIEDRCWRMLVVHDDAMLDGNARLNLATFVGTWMDDYANRIYMEAADKNMIDKDEYPKTAEIEDRCWRMLVVHDDAMLDGNARLNLATFVGTWMDDYANRIYMEAADKNMIDKDEYPKTAEIEDRCWRML************************************************************B.angulatum_GT102B.angulatum_LMGB.angulatum_DSMADLWNNLDIDHAIGTSTIGSSEACMLGGLALKRRWVKARKAAGLPTDKPNLVMSSAVQVCADLWNNPDIDHAIGTSTIGSSEACMLGGLALKRRWVKARKAAGLPTDKPNLVMSSAVQVCADLWNNPDIDHAIGTSTIGSSEACMLGGLALKRRWVKARKAAGLPTDKPNLVMSSAVQVC****** *****************************************************B.angulatum_GT102B.angulatum_LMGB.angulatum_DSMWEKFCNYFDVEPRFVPISEEHKVLDGYDLDKYVDENTIGVVAIMGVTYTGMYEPVQHISDWEKFCNYFDVEPRFVPISEEHKVLDGYDLDKYVDENTIGVVAIMGVTYTGMYEPVQHISDWEKFCNYFDVEPRFVPISEEHKVLDGYDLDKYVDENTIGVVAIMGVTYTGMYEPVQHISD************************************************************B.angulatum_GT102B.angulatum_LMGB.angulatum_DSMALDRIQEKTGLNIHIHVDAASGGMIAPFIQPDLAWDFRVKRVVSISTSGHKYGLVYPGLGALDRIQEKTGLNIHIHVDAASGGIIAPFIQPDLAWDFRVKRVVSISTSGHKYGLVYPGLGALDRIQEKTGLNIHIHVDAASGGIIAPFIQPDLAWDFRVKRVVSISTSGHKYGLVYPGLG***********************:************************************B.angulatum_GT102B.angulatum_LMGB.angulatum_DSMWVVWRSTADLPESLVFKVSYLGGEMPTFALNFSRPGAQVLLQYYMFLRLGVEGYRRVQQAWVVWRSTADLPESLVFKVSYLGGEMPTFALNFSRPGAQVLLQYYMFLRLGVEGYRRVQQAWVVWRSTADLPESLVFKVSYLGGEMPTFALNFSRPGAQVLLQYYMFLRLGVEGYRRVQQA************************************************************B.angulatum_GT102B.angulatum_LMGB.angulatum_DSMSHDVAKYLSSEIAAMDDFTLWNDGSDIPVFAWMLKDKPGRKWNLYDLQDRLRMKGWLVPASHDVAKYLSSEIAAMDDFTLWNDGSDIPVFAWMLKDKPGRKWNLYDLQDRLRMKGWLVPASHDVAKYLSSEIAAMDDFTLWNDGSDIPVFAWMLKDKPGRKWNLYDLQDRLRMKGWLVPA************************************************************B.angulatum_GT102B.angulatum_LMGB.angulatum_DSMYPMPVDLTDVTVQRIVVRNGFSHDLAESFLKDLKACVAYLDNLQAPMPSEAHVSGFHHYPMPVDLTDVTVQRIVVRNGFSHDLAESFLKDLKACVAYLDNLQAPMPSEAHVSGFHHYPMPVDLTDVTVQRIVVRNGFSHDLAESFLKDLKACVAYLDNLQAPMPSEAHVSGFHH**********************************************************150Выравнивание аминокислотных последовательностей белка антипортера (gadC) уштаммов Bifidobacterium angulatum.B.angulatum_GT102B.angulatum_LMGB.angulatum_JCMMSIGQLAILTVVAVASLRSLPAMADYGLASILLYLIPAVFFLVPTALVSAELATGWKGGVMSIGQLAILTVVAVASLRSLPAMADYGLASVLLYLIPAVFFLVPTALVSAELATGWKGGVMSIGQLAILTVVAVASLRSLPAMADYGLASVLLYLIPAVFFLVPTALVSAELATGWKGGV******************************:*****************************B.angulatum_GT102B.angulatum_LMGB.angulatum_JCMYVWVREAFGNRAGFVAIWLQWIQNVVWYPIQISFIAVSLSYVFGSGSLGNNGVYVAVVIIYVWVREAFGNRAGFVAIWLQWIQNVVWYPIQISFIAVSLSYVFGSGSLGNNGVYVAVVIIYVWVREAFGNRAGFVAIWLQWIQNVVWYPIQISFIAVSLSYVFGSGSLGNNGVYVAVVII************************************************************B.angulatum_GT102B.angulatum_LMGB.angulatum_JCMVLYWISTLVALRGGNLFAKVGSICGLIGTLLPAALLIILGIVWLCAGEPMHTSLHASALLVLYWISTLVALRGGNLFAKVGSICGLIGTLLPAALLIILGIVWLCAGEPMRTSLHASALLVLYWISTLVALRGGNLFAKVGSICGLIGTLLPAALLIILGIVWLCAGEPMRTSLHASALL**************************************************:*********B.angulatum_GT102B.angulatum_LMGB.angulatum_JCMPPWTGISSIVLIVSNVLAYAGMEVNAVH AND MKDPGREFPRATVLSTVLILLVLVLPTLSPPWTGISSIVLIVSNVLAYAGMEVNAVH AND MKDPGREFPRATVLSTVLILLVLVLPTLSPPWTGISSIVLIVSNVLAYAGMEVNAVH AND MKDPGREFPRATVLSTVLILLVLVLPTLS************************************************************B.angulatum_GT102B.angulatum_LMGB.angulatum_JCMIAFAVPHRELGLIDGINLAFKEFFDHFGMDWGVPVISLLIALGAFSSVITWIAGPSRGLLIAFAVPHRELGLIDGINLAFKEFFDHFGMDWGMPVISLLIALGAFSSVITWIAGPSRGLLIAFAVPHRELGLIDGINLAFKEFFDHFGMDWGMPVISLLIALGAFSSVITWIAGPSRGLL********************************:***************************B.angulatum_GT102B.angulatum_LMGB.angulatum_JCMAAARTGLMPPMLQKRNAAGVQEGILLAQGVIVTILALLFVLIPNGNTAFATLVDMATALYAAARTGLMPPMLQRRNAAGVQEGILLAQGVIVTILALLFVLIPNGNTAFATLVDMATALYAAARTGLMPPMLQRRNAAGVQEGILLAQGVIVTILALLFVLIPNGNTAFATLVDMATALY*************:**********************************************B.angulatum_GT102B.angulatum_LMGB.angulatum_JCMLMMYMMMFAAAIRLRISHPEVVRTYRVPALNWIAGIGFVAAAAAFVLAFVRPAGFSGMSSLMMYMMMFAAAIRLRISHPEVVRTYRVPALNWIAGIGFVAAAAAFVLAFVRPAGFSGMSSLMMYMMMFAAAIRLRISHPEVVRTYRVPALNWIAGIGFVAAAAAFVLAFVRPAGFSGMSS************************************************************B.angulatum_GT102B.angulatum_LMGB.angulatum_JCMLGYALLVALVVAVLGVPPLIMYALRRTDWDLRSDRDKRDSSSILVNPTKLGYALLVALVVAVLGVPPLIMYALRRTDWDLRSDRDKRDSSSILVNPTKLGYALLVALVVAVLGVPPLIMYALRRTDWDLRSDRDKRDSSSILVNPTK*************************************************151Выравнивание аминокислотных последовательностей белка глютаматдекарбоксилазыB(gadB) у штаммов Bifidobacterium adolescentis.B.adolescentis_150B.adolescentis_BBMN23B.adolescentis_L2-32B.adolescentis_22LB.adolescentis_DSM_20087B.adolescentis_2789VEINPLFARPKEAQAFSKFTIPQKSSLPETAYQVVHDEAMLDGNARLNLATFVSTWMDDHVEINPLFARPKEAQAFSKFTIPQKSSLPETAYQVVHDEAMLDGNARLNLATFVSTWMDDHVEINPLFARPKEAQAFSKFTIPQKGSLPETAYQVVHDEAMLDGNARLNLATFVSTWMDDHVEINPLFARPKEAQAFSKFTIPQKSSLPETAYQVVHDEAMLDGNARLNLATFVSTWMDDHVEINPLFARPKEAQAFSKFTIPQKGSLPETAYQVVHDEAMLDGNARLNLATFVSTWMDDHVEINPLFARPKEAQAFSKFTIPQKGSLPETAYQVVHDEAMLDGNARLNLATFVSTWMDDH************************.***********************************B.adolescentis_150B.adolescentis_BBMN23B.adolescentis_L2-32B.adolescentis_22LB.adolescentis_DSM_20087B.adolescentis_2789ANRLYMEAADKNMIDKDEYPKTAEVESRCWHMLADLWHAPDPMNAIGTSTIGSSEACMLGANRLYMEAADKNMIDKDEYPKTAEVESRCWHMLADLWHAPDPMNAIGTSTIGSSEACMLGANRLYMEAADKNMIDKDEYPKTAEVESRCWHMLADLWHAPDPMNAIGTSTIGSSEACMLGANRLYMEAADKNMIDKDEYPKTAEVESRCWHMLADLWHAPDPMNAIGTSTIGSSEACMLGANRLYMEAADKNMIDKDEYPKTAEVESRCWHMLADLWHAPDPMNAIGTSTIGSSEACMLGANRLYMEAANKNMIDKDEYPKTAEVESRCWHMLADLWHAPDPMNAIGTSTIGSSEACMLG*********:**************************************************B.adolescentis_150B.adolescentis_BBMN23B.adolescentis_L2-32B.adolescentis_22LB.adolescentis_DSM_20087B.adolescentis_2789GLALKRRWKEAREKADLPTDHPNLVMSSAVQVCWEKFCNYFDVEPRYVPISEDHKVLDGHGLALKRRWKEAREKADLPTDHPNLVMSSAVQVCWEKFCNYFDVEPRYVPISEDHKVLDGHGLALKRRWKEAREKADLPTDHPNLVMSSAVQVCWEKFCNYFDVEPRYVPISEDHKVLDGHGLALKRRWKEAREKADLPTDHPNLVMSSAVQVCWEKFCNYFDVEPRYVPISEDHKVLDGHGLALKRRWKEAREKADLPTDRPNLVMSSAVQVCWEKFCNYFDVEPRYVPISEDHKVLDGHGLALKRRWKEAREKADLPTDRPNLVMSSAVQVCWEKFCNYFDVEPRYVPISEDHKVLDGH********************.***************************************B.adolescentis_150B.adolescentis_BBMN23B.adolescentis_L2-32B.adolescentis_22LB.adolescentis_DSM_20087B.adolescentis_2789DLDKYVDENTIGVVAIMGVTYTGMYEPVEQISEALDRIEERTGLDVRIHVDGASGGMIAPDLDKYVDENTIGVVAIMGVTYTGMYEPVEQISEALDRIEERTGLDVRIHVDGASGGMIAPDLDKYVDENTIGVVAIMGVTYTGMYEPVEQISEALDRIEERTGLDVRIHVDGASGGMIAPDLDKYVDENTIGVVAIMGVTYTGMYEPVEQISEALDRIEERTGLDVRIHVDGASGGMIAPDLDKYVDENTIGVVAIMGVTYTGMYEPVEQISEALDRIEERTGLDVRIHVDGASGGMIAPDLDKYVDENTIGVVAIMGVTYTGMYEPVEQISEALDRIEERTGLDVRIHVDGASGGMIAP************************************************************B.adolescentis_150B.adolescentis_BBMN23B.adolescentis_L2-32B.adolescentis_22LB.adolescentis_DSM_20087B.adolescentis_2789FIQPDLAWDFRVKRVYSISTSGHKYGLVYPGLGWVVWRETADLPESLIFKVSYLGGEMPTFIQPDLAWDFRVKRVYSISTSGHKYGLVYPGLGWVVWRETADLPESLIFKVSYLGGEMPTFIQPDLAWDFRVKRVYSISTSGHKYGLVYPGLGWVVWRETADLPESLIFKVSYLGGEMPTFIQPDLAWDFRVKRVYSISTSGHKYGLVYPGLGWIVWRETADLPESLIFKVSYLGGEMPTFIQPDLAWDFRVKRVYSISTSGHKYGLVYPGLGWIVWRETADLPESLIFKVSYLGGEMPTFIQPDLAWDFRVKRVYSISTSGHKYGLVYPGLGWIVWRETADLPESLIFKVSYLGGEMPT**********************************:*************************B.adolescentis_150B.adolescentis_BBMN23B.adolescentis_L2-32B.adolescentis_22LB.adolescentis_DSM_20087B.adolescentis_2789FALNFSRPGAQVLLQYYMFLRLGFDGYRRVQQTSHDVAKYLSGEIEQMDDFTLWNDGSDIFALNFSRPGAQVLLQYYMFLRLGFDGYRRVQQTSHDVAKYLSGEIEQMDDFTLWNDGSDIFALNFSRPGAQVLLQYYMFLRLGFDGYRRVQQTSHDVAKYLSGEIEQMDDFTLWNDGSDIFALNFSRPGAQVLLQYYMFLRLGFDGYRRVQQTSHDVAKYLSGEIEQMDDFTLWNDGSDIFALNFSRPGAQVLLQYYMFLRLGFDGYRRVQQTSHDVAKYLSGEIEQMDDFTLWNDGSDIFALNFSRPGAQVLLQYYMFLRLGFDGYRRVQQTSHDMAKYLSGEIEQMDDFTLWNDGSDI************************************:***********************B.adolescentis_150B.adolescentis_BBMN23B.adolescentis_L2-32B.adolescentis_22LB.adolescentis_DSM_20087B.adolescentis_2789PVFAWMLNDKPDRKWNLYDLQDRLRMKGWLVPAYPMPVDLTQVTVQRIVVRNGFSHDMAEPVFAWMLNDKPDRKWNLYDLQDRLRMKGWLVPAYPMPVDLTQVTVQRIVVRNGFSHDMAEPVFAWMLNDKPDRKWNLYDLQDRLRMKGWLVPAYPMPVDLTQVTVQRIVVRNGFSHDMAEPVFAWMLNDKPDRKWNLYDLQDRLRMKGWLVPAYPMPVDLTQVTVQRIVVRNGFSHDMAEPVFAWMLNDKPDRKWNLYDLQDRLRMKGWLVPAYPMPVDLTQVTVQRIVVRNGFSHDMAEPVFAWMLNDKPDRKWNLYDLQDRLRMKGWLVPAYPMPVDLTQVTVQRIVVRNGFSHDMAE************************************************************B.adolescentis_150B.adolescentis_BBMN23B.adolescentis_L2-32B.adolescentis_22LB.adolescentis_DSM_20087B.adolescentis_2789AFIKDLKSCVKYLDGLRSPMPSEARASGFHHAFIKDLKSCVKYLDGLRSPMPSEARASGFHHAFIKDLKSCVKYLDGLRSPMPSEARASGFHHAFIKDLKSCVKYLDGLRSPMPSEARASGFHHAFIKDLKSCVKYLDGLRSPMPSEARASGFHHAFIKDLKSCVKYLDGLRSPMPSEARASEFHH*************************** ***152Выравнивание аминокислотных последовательностей белка антипортера (gadC) уштаммов Bifidobacterium adolescentis.B.adolescentis_150B.adolescentis_2789B.adolescentis_BBMN23B.adolescentis_L2-32B.adolescentis_DSM20087B.adolescentis_22LMTVSQLAMLTVVAVASLRSLPAMADYGLASILLYLIPAVVFLVPTALVAAELATGWKGGVMTVSQLAMLTVVAVASLRSLPAMADYGLASILLYLIPAVVFLVPTALVAAELATGWKGGVMTVSQLAMLTVVAVASLRSLPAMADYGLASILLYLIPAVVFLVPTALVAAELATGWKGGVMTVSQLAMLTVVAVASLRSLPAMADYGLASILLYLIPAVVFLVPTALVAAELATGWKGGVMTVSQLAMLTVVAVASLRSLPAMADYGLASILLYLIPAVVFLVPTALVAAELATGWKGGVMTVSQLAMLTVVAVASLRSLPAMADYGLASILLYLIPAVVFLVPTALVAAELATGWKGGV************************************************************B.adolescentis_150B.adolescentis_2789B.adolescentis_BBMN23B.adolescentis_L2-32B.adolescentis_DSM20087B.adolescentis_22LYVWVREAFGNRIGFLAIWLQWIQNVVWYPIQIAFIAVSLSYVFGMGGLGNNGVYVAAVIIYVWVREAFGNRIGFLAIWLQWIQNVVWYPIQIAFIAVSLSYVFGMGGLGNNGVYVAAVIIYVWVREAFGNRIGFLAIWLQWIQNVVWYPIQIAFIAVSLSYVFGMGGLGNNGVYVAAVIIYVWVREAFGNRIGFLAIWLQWIQNVVWYPIQIAFIAVSLSYVFGMGGLGNNGVYVAAVIIYVWVREAFGNRIGFLAIWLQWIQNVVWYPIQIAFIAVSLSYVFGMGGLGNNGVYVAAVIIYVWVREAFGNRIGFLAIWLQWIQNVVWYPIQIAFIAVSLSYVFGMGGLGNNGVYVAAVII************************************************************B.adolescentis_150B.adolescentis_2789B.adolescentis_BBMN23B.adolescentis_L2-32B.adolescentis_DSM20087B.adolescentis_22LVLYWASTMVALRGGNLFAKVGSISGLIGTLFPALLLIVFGIIWLAIGKPVQTSLHASALLVLYWASTMVALRGGNLFAKVGSISGLIGTLFPALLLIVFGIIWLAIGKPVQTSLHASALLVLYWASTMVALRGGNLFAKVGSISGLIGTLFPALLLIVFGIIWLAIGKPVQTSLHASALLVLYWASTMVALRGGNLFAKVGSISGLIGTLFPALLLIVFGIIWLAIGKPVQTSLHASALLVLYWASTMVALRGGNLFAKVGSISGLIGTLFPALLLIVFGIIWLAIGKPVQTSLHASALLVLYWASTMVALRGGNLFAKVGAISGLIGTLFPALLLIVFGIIWLAIGKPVQTSLHASALL*********************:**************************************B.adolescentis_150B.adolescentis_2789B.adolescentis_BBMN23B.adolescentis_L2-32B.adolescentis_DSM20087B.adolescentis_22LPPWTGIASIVLIVSNVLAYAGMEVNAVH AND LEHPGRQFPRAIALATALILLVLVLPTLAPPWTGIASIVLIVSNVLAYAGMEVNAVH AND LEHPGRQFPRAIALATALILLVLVLPTLAPPWTGIASIVLIVSNVLAYAGMEVNAVH AND LEHPGRQFPRAIALATALILLVLVLPTLAPPWTGIASIVLIVSNVLAYAGMEVNAVH AND LEHPGRQFPRAIALATALILLVLVLPTLAPPWTGIASIVLIVSNVLAYAGMEVNAVH AND LEHPGRQFPRAIALATALILLVLVLPTLAPPWTGIASIVLIVSNVLAYAGMEVNAVH AND LEHPGRQFPRAIALATALILLVLVLPTLA************************************************************B.adolescentis_150B.adolescentis_2789B.adolescentis_BBMN23B.adolescentis_L2-32B.adolescentis_DSM20087B.adolescentis_22LIAFAVPHRELGLIDGINLAFREFFDHFGMGWGTPVISLLIALGAFASVVAWIAGPSRGLLIAFAVPHRELGLIDGINLAFREFFDHFGMGWGTPVISLLIALGAFASVVAWIAGPSRGLLIAFAVPHRELGLIDGINLAFREFFDHFGMGWGTPVISLLIALGAFASVVAWIAGPSRGLLIAFAVPHRELGLIDGINLAFREFFDHFGMGWGTPVISLLIALGAFASVVAWIAGPSRGLLIAFAVPHRELGLIDGINLAFREFFDHFGMGWGTPVISLLIALGAFASVVAWIAGPSRGLLIAFAVPHRELGLIDGINLAFREFFDHFGMGWGTPVISLLIALGAFASVVAWIAGPSRGLL************************************************************B.adolescentis_150B.adolescentis_2789B.adolescentis_BBMN23B.adolescentis_L2-32B.adolescentis_DSM20087B.adolescentis_22LAAARTGLMPPALQKRNAHDVQEGILIPQGIIVTVLALLFVLIPNGNTAFATLVDMATALYAAARTGLMPPALQKRNAHDVQEGILIPQGIIVTVLALLFVLIPNGNTAFATLVDMATALYAAARTGLMPPALQKRNAHDVQEGILIPQGIIVTVLALLFVLIPNGNTAFATLVDMATALYAAARTGLMPPALQKRNAHDVQEGILIPQGIIVTVLALLFVLIPNGNTAFATLVDMATALYAAARTGLMPPALQKRNAHDVQEGILIPQGIIVTVLALLFVLIPNGNTAFATLVDMATALYAAARTGLMPPALQKRNAHDVQEGILIPQGIIVTVLALLFVLIPNGNTAFATLVDMATALY************************************************************B.adolescentis_150B.adolescentis_2789B.adolescentis_BBMN23B.adolescentis_L2-32B.adolescentis_DSM20087B.adolescentis_22LLVMYMLMFAAAIRLRNTHPEVRRTYRVPAIRLVAGVGFVASAAAFVLTFVRPAGFTGLDSLVMYMLMFAAAIRLRNTHPEVRRTYRVPAIRLVAGVGFVASAAAFVLTFVRPAGFTGLDSLVMYMLMFAAAIRLRNTHPEVRRTYRVPAIRLVAGVGFVASAAAFVLTFVRPAGFTGLDSLVMYMLMFAAAIRLRNTHPEVRRTYRVPAIRLVAGVGFVASAAAFVLTFVRPAGFTGLDSLVMYMLMFAAAIRLRNTHPEVRRTYRVPAIRLVAGVGFVASAAAFVLTFVRPAGFTGLDSLVMYMLMFAAAIRLRDTHPEVRRTYRVPAIRLVAGVGFVASAAAFVLTFVRPAGFTGLDS***************:********************************************B.adolescentis_150B.adolescentis_2789B.adolescentis_BBMN23B.adolescentis_L2-32B.adolescentis_DSM20087B.adolescentis_22LVSYAILVAVVVLVLGLPPLVLYGMRKPGWDLRSDAERNTDTYDVLVNPEYVSYAILVAVVVLVLGLPPLVLYGMRKPGWDLRSDAERNTDTYDVLVNPEYVSYAILVAVVVLVLGLPPLVLYGMRKPGWDLRSDAERNTDTYDVLVNPEYVSYAILVAVVVLVLGLPPLVLYGMRKPGWDLRSDAERNTDTYDVLVNPEYVSYAILVAVVVLVLGLPPLVLYGMRKPGWDLRSDAERNTDTYDVLVNPEYVSYAILVAVVVLVLGLPPLVLYGMRKPGWDLRSDAERNTDTYDVLVNPEY**************************************************153БЛАГОДАРНОСТИФедеральное государственное бюджетное учреждение наукиИнститут общей генетики им.

Н.И. Вавилова Российской академии наукЛабораториия генетики микроорганизмовд.б.н. Даниленко Валерий Николаевичд.б.н. Полуэктова Елена Ульриховнак.б.н. Аверина Ольга Викторовнак.б.н. Незаметдинова Венера Закировнак.б.н. Климина Ксения МихайловнаДьячкова Марина ВладимировнаЕпифанова Майя ВалерьевнаФедеральное государственное автономное образовательноеучреждение высше го образования Российский Университет ДружбыНародов (РУДН)Кафедра системной экологиид.б.н.

Орлова Валентина СергеевнаФедеральное государственное бюджетное учреждение наукиИнститут биоорганической химии им. академиков М.М. Шемякина и Ю.А.Овчинникова Российской академии наукЛаборатория изотопных методов анализак.х.н. Скоблов Юрий Самойлович154.